Gene Ontology

Gene Info

  • Species:Mouse (Mus musculus)
  • GeneID:12335
  • Symbol:Capn3
  • Description:calpain 3

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
12335 GO:0004198 IDA enables calcium-dependent cysteine-type endopeptidase activity 15138196 Function
12335 GO:0005509 IDA enables calcium ion binding 20460380 Function
12335 GO:0005515 IPI enables protein binding 14741210,15138196,19924298,20405035 Function
12335 GO:0008307 IMP enables structural constituent of muscle 18676612 Function
12335 GO:0031402 IDA enables sodium ion binding 20460380 Function
12335 GO:0060090 IMP enables molecular adaptor activity 18676612 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
12335 GO:0005737 IDA located_in cytoplasm 18073330,20139084 Component
12335 GO:0005829 IDA located_in cytosol 18676612 Component
12335 GO:0005886 IDA located_in plasma membrane 18676612 Component
12335 GO:0032991 IDA part_of protein-containing complex 18676612 Component

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
12335 GO:0006508 IDA acts_upstream_of_or_within proteolysis 15138196 Process
12335 GO:0006508 IDA involved_in proteolysis 20460380 Process
12335 GO:0012501 IDA involved_in programmed cell death 20460380 Process
12335 GO:0014718 IDA involved_in positive regulation of satellite cell activation involved in skeletal muscle regeneration 20139084 Process
12335 GO:0030239 IMP acts_upstream_of_or_within myofibril assembly 15138196 Process
12335 GO:0043066 IMP involved_in negative regulation of apoptotic process 18073330 Process
12335 GO:0043122 IMP involved_in regulation of I-kappaB kinase/NF-kappaB signaling 18073330 Process
12335 GO:0045214 IMP acts_upstream_of_or_within sarcomere organization 15138196 Process
12335 GO:0045661 IDA involved_in regulation of myoblast differentiation 20139084 Process
12335 GO:0045862 IDA involved_in positive regulation of proteolysis 20139084 Process
12335 GO:0045892 IDA involved_in negative regulation of DNA-templated transcription 20139084 Process
12335 GO:0045893 IMP involved_in positive regulation of DNA-templated transcription 18073330 Process
12335 GO:0051092 IMP involved_in positive regulation of NF-kappaB transcription factor activity 18073330 Process
12335 GO:0051281 IMP involved_in positive regulation of release of sequestered calcium ion into cytosol 18676612 Process
12335 GO:0061061 IMP involved_in muscle structure development 18676612 Process
12335 GO:0065003 IMP involved_in protein-containing complex assembly 18676612 Process
12335 GO:0070315 IDA involved_in G1 to G0 transition involved in cell differentiation 20139084 Process
12335 GO:0071277 IDA involved_in cellular response to calcium ion 20460380 Process
12335 GO:0071472 IDA involved_in cellular response to salt stress 20460380 Process
12335 GO:0072657 IMP involved_in protein localization to membrane 18676612 Process