Gene Ontology

Gene Info

  • Species:Mouse (Mus musculus)
  • GeneID:12367
  • Symbol:Casp3
  • Description:caspase 3

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
12367 GO:0001782 IMP acts_upstream_of_or_within B cell homeostasis 12970760 Process
12367 GO:0006915 IMP acts_upstream_of_or_within apoptotic process 9512515,12970760 Process
12367 GO:0006974 IDA acts_upstream_of_or_within DNA damage response 11092819 Process
12367 GO:0007507 IGI acts_upstream_of_or_within heart development 16469926 Process
12367 GO:0007605 IMP acts_upstream_of_or_within sensory perception of sound 11374883 Process
12367 GO:0008627 IDA involved_in intrinsic apoptotic signaling pathway in response to osmotic stress 21716255 Process
12367 GO:0009411 IDA acts_upstream_of_or_within response to UV 11092819 Process
12367 GO:0009411 IGI acts_upstream_of_or_within response to UV 16469926 Process
12367 GO:0009611 IDA acts_upstream_of_or_within response to wounding 14507967 Process
12367 GO:0010033 IDA acts_upstream_of_or_within response to organic substance 17475835 Process
12367 GO:0016485 IDA acts_upstream_of_or_within protein processing 15231831 Process
12367 GO:0030216 IMP acts_upstream_of_or_within keratinocyte differentiation 15068794 Process
12367 GO:0030889 IMP acts_upstream_of_or_within negative regulation of B cell proliferation 12970760 Process
12367 GO:0034349 IMP acts_upstream_of_or_within glial cell apoptotic process 11549719 Process
12367 GO:0043029 IMP acts_upstream_of_or_within T cell homeostasis 12970760 Process
12367 GO:0043065 IDA involved_in positive regulation of apoptotic process 19626005,21716255 Process
12367 GO:0044346 IDA acts_upstream_of_or_within fibroblast apoptotic process 12847083 Process
12367 GO:0044346 IMP acts_upstream_of_or_within fibroblast apoptotic process 16469926 Process
12367 GO:0045165 IMP acts_upstream_of_or_within cell fate commitment 15068794 Process
12367 GO:0045736 IMP acts_upstream_of_or_within negative regulation of cyclin-dependent protein serine/threonine kinase activity 12970760 Process
12367 GO:0045786 IMP acts_upstream_of_or_within negative regulation of cell cycle 12970760 Process
12367 GO:0046007 IMP acts_upstream_of_or_within negative regulation of activated T cell proliferation 12970760 Process
12367 GO:0051402 IDA acts_upstream_of_or_within neuron apoptotic process 12427836,15231831 Process
12367 GO:0051402 IGI acts_upstream_of_or_within neuron apoptotic process 10618441 Process
12367 GO:0051402 IMP acts_upstream_of_or_within neuron apoptotic process 10479688,10618441,11549719 Process
12367 GO:0061713 IMP acts_upstream_of_or_within anterior neural tube closure 21515572 Process
12367 GO:0071310 IDA acts_upstream_of_or_within cellular response to organic substance 12606450 Process
12367 GO:0097191 IDA involved_in extrinsic apoptotic signaling pathway 19626005 Process
12367 GO:0097194 IDA acts_upstream_of_or_within execution phase of apoptosis 12124386,12954857,15456877 Process
12367 GO:0097194 IGI acts_upstream_of_or_within execution phase of apoptosis 16469926 Process
12367 GO:0097194 IMP acts_upstream_of_or_within execution phase of apoptosis 11549719 Process
12367 GO:0097194 IMP involved_in execution phase of apoptosis 8934524 Process
12367 GO:1902512 IDA involved_in positive regulation of apoptotic DNA fragmentation 9545256 Process
12367 GO:1904019 IDA acts_upstream_of_or_within epithelial cell apoptotic process 17901126 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
12367 GO:0004175 IDA enables endopeptidase activity 12124386 Function
12367 GO:0004190 IDA enables aspartic-type endopeptidase activity 15231831,23727203 Function
12367 GO:0004197 IDA enables cysteine-type endopeptidase activity 14657025,15456877,19759058 Function
12367 GO:0004861 IMP enables cyclin-dependent protein serine/threonine kinase inhibitor activity 12970760 Function
12367 GO:0005515 IPI enables protein binding 17124493,18585351,19759058 Function
12367 GO:0008233 IDA enables peptidase activity 12427836,12954857,13679151,14561754 Function
12367 GO:0008233 IMP enables peptidase activity 11549719,12970760,16469926 Function
12367 GO:0008234 IDA enables cysteine-type peptidase activity 17544522 Function
12367 GO:0097153 IDA enables cysteine-type endopeptidase activity involved in apoptotic process 16183742,24378336,25231987 Function
12367 GO:0097200 IDA enables cysteine-type endopeptidase activity involved in execution phase of apoptosis 12124386 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
12367 GO:0005634 IDA located_in nucleus 22358842 Component
12367 GO:0005737 IDA located_in cytoplasm 12477715,21716255,23861879,25139234 Component