Gene Ontology

Gene Info

  • Species:Mouse (Mus musculus)
  • GeneID:12567
  • Symbol:Cdk4
  • Description:cyclin-dependent kinase 4

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
12567 GO:0000307 IPI part_of cyclin-dependent protein kinase holoenzyme complex 12970760 Component
12567 GO:0005634 IDA located_in nucleus 8988060,10082561,12917627,15645444,21411630 Component
12567 GO:0005667 IDA part_of transcription regulator complex 10082561 Component
12567 GO:0005923 IDA located_in bicellular tight junction 21411630 Component
12567 GO:0097128 IPI part_of cyclin D1-CDK4 complex 17948060 Component
12567 GO:0097129 IDA part_of cyclin D2-CDK4 complex 7739547,8543804 Component

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
12567 GO:0004672 IDA enables protein kinase activity 12130539,12588994,21508411 Function
12567 GO:0004693 IDA enables cyclin-dependent protein serine/threonine kinase activity 12970171,12970760 Function
12567 GO:0005515 IPI enables protein binding 8033213,12124778,12130539,12588994,12970760,15107404,16413468,..... Function
12567 GO:0016301 IDA enables kinase activity 12124778 Function
12567 GO:0030332 IPI enables cyclin binding 23109711 Function

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
12567 GO:0006468 IDA acts_upstream_of_or_within protein phosphorylation 12124778,12588994 Process
12567 GO:0007165 IDA acts_upstream_of_or_within signal transduction 12130539 Process
12567 GO:0051726 IDA acts_upstream_of_or_within regulation of cell cycle 12588994 Process
12567 GO:0061469 IMP acts_upstream_of_or_within regulation of type B pancreatic cell proliferation 12917627 Process
12567 GO:0071222 IDA acts_upstream_of_or_within cellular response to lipopolysaccharide 8543804 Process
12567 GO:0071353 IDA acts_upstream_of_or_within cellular response to interleukin-4 8543804 Process
12567 GO:1904628 IDA acts_upstream_of_or_within cellular response to phorbol 13-acetate 12-myristate 8543804 Process
12567 GO:1904637 IDA acts_upstream_of_or_within cellular response to ionomycin 8543804 Process