Gene Ontology

Gene Info

  • Species:Mouse (Mus musculus)
  • GeneID:12568
  • Symbol:Cdk5
  • Description:cyclin-dependent kinase 5

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
12568 GO:0000307 IPI part_of cyclin-dependent protein kinase holoenzyme complex 18325333 Component
12568 GO:0005634 IDA located_in nucleus 8891282,9191048,15096606,17591690 Component
12568 GO:0005730 IDA NOT located_in nucleolus 3627430 Component
12568 GO:0005737 IDA located_in cytoplasm 3627430,9191048,15096606 Component
12568 GO:0005829 IDA located_in cytosol 9202329,12496365 Component
12568 GO:0016533 IPI part_of protein kinase 5 complex 18325333 Component
12568 GO:0030027 IDA located_in lamellipodium 12496365 Component
12568 GO:0030175 IDA located_in filopodium 12496365 Component
12568 GO:0030424 IDA located_in axon 3627430 Component

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
12568 GO:0001764 IMP acts_upstream_of_or_within neuron migration 10407039,15067135 Process
12568 GO:0001963 IMP acts_upstream_of_or_within synaptic transmission, dopaminergic 14769920 Process
12568 GO:0006468 IDA acts_upstream_of_or_within protein phosphorylation 11517264,12372285,15123626,15489224,17194758 Process
12568 GO:0006468 IGI acts_upstream_of_or_within protein phosphorylation 17060449 Process
12568 GO:0006468 IMP acts_upstream_of_or_within protein phosphorylation 17591690 Process
12568 GO:0006886 IMP acts_upstream_of_or_within intracellular protein transport 8855328 Process
12568 GO:0006915 IDA acts_upstream_of_or_within apoptotic process 9126296 Process
12568 GO:0007160 IDA acts_upstream_of_or_within cell-matrix adhesion 12496365 Process
12568 GO:0007409 IMP acts_upstream_of_or_within axonogenesis 11163260 Process
12568 GO:0007416 IMP acts_upstream_of_or_within synapse assembly 18054859 Process
12568 GO:0007519 IDA acts_upstream_of_or_within skeletal muscle tissue development 9191048 Process
12568 GO:0008045 IMP acts_upstream_of_or_within motor neuron axon guidance 16203963 Process
12568 GO:0008306 IMP acts_upstream_of_or_within associative learning 11978846 Process
12568 GO:0008542 IMP acts_upstream_of_or_within visual learning 17529984 Process
12568 GO:0014044 IMP acts_upstream_of_or_within Schwann cell development 16203963 Process
12568 GO:0016477 IDA acts_upstream_of_or_within cell migration 12496365 Process
12568 GO:0016477 IMP acts_upstream_of_or_within cell migration 17694053,18032654 Process
12568 GO:0018105 IDA acts_upstream_of_or_within peptidyl-serine phosphorylation 18054859 Process
12568 GO:0018105 IMP acts_upstream_of_or_within peptidyl-serine phosphorylation 18054859 Process
12568 GO:0018105 IMP involved_in peptidyl-serine phosphorylation 24607229 Process
12568 GO:0018107 IDA acts_upstream_of_or_within peptidyl-threonine phosphorylation 18054859 Process
12568 GO:0018107 IMP involved_in peptidyl-threonine phosphorylation 24607229 Process
12568 GO:0019233 IMP acts_upstream_of_or_within sensory perception of pain 17194758 Process
12568 GO:0021537 IMP acts_upstream_of_or_within telencephalon development 18032654 Process
12568 GO:0021549 IMP acts_upstream_of_or_within cerebellum development 11226314 Process
12568 GO:0021695 IMP acts_upstream_of_or_within cerebellar cortex development 8855328 Process
12568 GO:0021697 IMP acts_upstream_of_or_within cerebellar cortex formation 10407039 Process
12568 GO:0021766 IMP acts_upstream_of_or_within hippocampus development 11517264 Process
12568 GO:0021819 IMP acts_upstream_of_or_within layer formation in cerebral cortex 11517264 Process
12568 GO:0021954 IMP acts_upstream_of_or_within central nervous system neuron development 8855328 Process
12568 GO:0021987 IMP acts_upstream_of_or_within cerebral cortex development 9698328 Process
12568 GO:0022038 IMP acts_upstream_of_or_within corpus callosum development 18032654 Process
12568 GO:0030182 IMP acts_upstream_of_or_within neuron differentiation 16237170 Process
12568 GO:0030334 IMP acts_upstream_of_or_within regulation of cell migration 12941275 Process
12568 GO:0030517 IGI acts_upstream_of_or_within negative regulation of axon extension 22573681 Process
12568 GO:0030900 IMP acts_upstream_of_or_within forebrain development 17694053 Process
12568 GO:0031397 IMP acts_upstream_of_or_within negative regulation of protein ubiquitination 17591690 Process
12568 GO:0031914 IMP acts_upstream_of_or_within negative regulation of synaptic plasticity 17529984 Process
12568 GO:0032092 IMP acts_upstream_of_or_within positive regulation of protein binding 18054859 Process
12568 GO:0032801 IMP acts_upstream_of_or_within receptor catabolic process 17529984 Process
12568 GO:0035249 IMP acts_upstream_of_or_within synaptic transmission, glutamatergic 14769920 Process
12568 GO:0035418 IMP acts_upstream_of_or_within protein localization to synapse 18054859 Process
12568 GO:0042220 IMP acts_upstream_of_or_within response to cocaine 14769920 Process
12568 GO:0042501 IDA acts_upstream_of_or_within serine phosphorylation of STAT protein 15096606 Process
12568 GO:0043113 IMP acts_upstream_of_or_within receptor clustering 16203963 Process
12568 GO:0045786 IMP acts_upstream_of_or_within negative regulation of cell cycle 16237170 Process
12568 GO:0045860 IMP acts_upstream_of_or_within positive regulation of protein kinase activity 16203963 Process
12568 GO:0045956 IDA acts_upstream_of_or_within positive regulation of calcium ion-dependent exocytosis 15123626 Process
12568 GO:0046826 IMP acts_upstream_of_or_within negative regulation of protein export from nucleus 17591690 Process
12568 GO:0048148 IMP acts_upstream_of_or_within behavioral response to cocaine 18032670 Process
12568 GO:0048813 IMP acts_upstream_of_or_within dendrite morphogenesis 12372285,17143272 Process
12568 GO:0051402 IMP acts_upstream_of_or_within neuron apoptotic process 17591690 Process
12568 GO:0051649 IMP acts_upstream_of_or_within establishment of localization in cell 18054859 Process
12568 GO:0051966 IMP involved_in regulation of synaptic transmission, glutamatergic 24607229 Process
12568 GO:0060078 IMP acts_upstream_of_or_within regulation of postsynaptic membrane potential 16203963 Process
12568 GO:0060079 IMP acts_upstream_of_or_within excitatory postsynaptic potential 17529984 Process
12568 GO:0061001 IMP involved_in regulation of dendritic spine morphogenesis 17143272 Process
12568 GO:0070509 IMP acts_upstream_of_or_within calcium ion import 18054859 Process
12568 GO:0090314 IMP acts_upstream_of_or_within positive regulation of protein targeting to membrane 18054859 Process
12568 GO:1903076 IMP involved_in regulation of protein localization to plasma membrane 24607229 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
12568 GO:0002039 IPI enables p53 binding 17591690 Function
12568 GO:0004672 IDA enables protein kinase activity 9126296,9202329,11226314,11343650,11517264,12077184,12372285,1..... Function
12568 GO:0004672 IMP enables protein kinase activity 14769920,16203963,18054859 Function
12568 GO:0004674 IDA enables protein serine/threonine kinase activity 12941275,15489224,18054859 Function
12568 GO:0005176 IDA enables ErbB-2 class receptor binding 11276227 Function
12568 GO:0005515 IPI enables protein binding 11276227,12496365,12972605,15096606,17341134,17529984,18054859..... Function
12568 GO:0030549 IDA enables acetylcholine receptor activator activity 11276227 Function
12568 GO:0043125 IDA enables ErbB-3 class receptor binding 11276227 Function
12568 GO:0051879 IPI enables Hsp90 protein binding 17517623 Function