Gene Ontology

Gene Info

  • Species:Mouse (Mus musculus)
  • GeneID:12772
  • Symbol:Ccr2
  • Description:chemokine (C-C motif) receptor 2

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
12772 GO:0002548 IMP acts_upstream_of_or_within monocyte chemotaxis 23913046 Process
12772 GO:0002724 IMP involved_in regulation of T cell cytokine production 28507030 Process
12772 GO:0002827 IMP involved_in positive regulation of T-helper 1 type immune response 10657654 Process
12772 GO:0002829 IMP involved_in negative regulation of type 2 immune response 14662900 Process
12772 GO:0006954 IMP acts_upstream_of_or_within inflammatory response 10946288 Process
12772 GO:0006955 IMP acts_upstream_of_or_within immune response 10854218,10946288,10993920 Process
12772 GO:0006959 IMP acts_upstream_of_or_within humoral immune response 10899907 Process
12772 GO:0006968 IMP acts_upstream_of_or_within cellular defense response 9366570 Process
12772 GO:0010574 IMP involved_in regulation of vascular endothelial growth factor production 14566334 Process
12772 GO:0010820 IDA involved_in positive regulation of T cell chemotaxis 18586982 Process
12772 GO:0016525 IMP involved_in negative regulation of angiogenesis 14566334 Process
12772 GO:0019233 IMP acts_upstream_of_or_within sensory perception of pain 12808141 Process
12772 GO:0019233 IMP involved_in sensory perception of pain 29993042 Process
12772 GO:0019725 IDA involved_in cellular homeostasis 18832716 Process
12772 GO:0030097 IMP acts_upstream_of_or_within hemopoiesis 9366570 Process
12772 GO:0032729 IMP involved_in positive regulation of type II interferon production 14662900 Process
12772 GO:0032743 IMP involved_in positive regulation of interleukin-2 production 14662900 Process
12772 GO:0032760 IMP involved_in positive regulation of tumor necrosis factor production 18832716 Process
12772 GO:0035696 IMP involved_in monocyte extravasation 29632244 Process
12772 GO:0035705 IDA involved_in T-helper 17 cell chemotaxis 18586982 Process
12772 GO:0043310 IMP involved_in negative regulation of eosinophil degranulation 14662900 Process
12772 GO:0045580 IMP involved_in regulation of T cell differentiation 28507030 Process
12772 GO:0046641 IMP involved_in positive regulation of alpha-beta T cell proliferation 14662900 Process
12772 GO:0048873 IMP acts_upstream_of_or_within homeostasis of number of cells within a tissue 9342361 Process
12772 GO:0050727 IMP involved_in regulation of inflammatory response 28507030 Process
12772 GO:0050729 IDA involved_in positive regulation of inflammatory response 20234092 Process
12772 GO:0050870 IMP involved_in positive regulation of T cell activation 14662900 Process
12772 GO:0051968 IMP involved_in positive regulation of synaptic transmission, glutamatergic 29993042 Process
12772 GO:0061756 IMP acts_upstream_of_or_within leukocyte adhesion to vascular endothelial cell 9342361 Process
12772 GO:0071675 IMP acts_upstream_of_or_within regulation of mononuclear cell migration 10899907,10993920 Process
12772 GO:0090026 IMP involved_in positive regulation of monocyte chemotaxis 18832716 Process
12772 GO:0090265 IMP involved_in positive regulation of immune complex clearance by monocytes and macrophages 14566334 Process
12772 GO:0090594 IMP involved_in inflammatory response to wounding 24806994,29632244 Process
12772 GO:0097350 IMP acts_upstream_of_or_within neutrophil clearance 9342361 Process
12772 GO:0120162 IMP involved_in positive regulation of cold-induced thermogenesis 24906148 Process
12772 GO:1903238 IMP acts_upstream_of_or_within positive regulation of leukocyte tethering or rolling 9342361 Process
12772 GO:1905517 IMP involved_in macrophage migration 24806994 Process
12772 GO:1905521 IMP acts_upstream_of_or_within regulation of macrophage migration 10854218 Process
12772 GO:2000404 IMP acts_upstream_of_or_within regulation of T cell migration 10854218 Process
12772 GO:2000412 IMP involved_in positive regulation of thymocyte migration 29930553 Process
12772 GO:2000439 IMP involved_in positive regulation of monocyte extravasation 14566334 Process
12772 GO:2000451 IMP involved_in positive regulation of CD8-positive, alpha-beta T cell extravasation 14662900 Process
12772 GO:2000473 IMP involved_in positive regulation of hematopoietic stem cell migration 20234092 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
12772 GO:0005515 IPI enables protein binding 8662823 Function
12772 GO:0016493 IDA enables C-C chemokine receptor activity 8631787,8662823 Function
12772 GO:0019955 IPI enables cytokine binding 8631787 Function
12772 GO:0035715 IPI enables chemokine (C-C motif) ligand 2 binding 8662823 Function
12772 GO:0035716 IPI enables chemokine (C-C motif) ligand 12 binding 8996246 Function
12772 GO:0035717 IPI enables chemokine (C-C motif) ligand 7 binding 8662823 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
12772 GO:0009897 IDA located_in external side of plasma membrane 23610400 Component