Gene Ontology

Gene Info

• Species:Human (Homo sapiens)
• GeneID:1311
• Symbol:COMP
• Description:cartilage oligomeric matrix protein

Function

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
1311	GO:0002020	IPI	enables	protease binding	18485748	Function
1311	GO:0005509	IDA	enables	calcium ion binding	10852928,11084047	Function
1311	GO:0005515	IPI	enables	protein binding	12225811,15075323,16051604,16611630,17588949,18485748,25416956.....	Function
1311	GO:0005518	IDA	enables	collagen binding	11084047	Function
1311	GO:0008201	IDA	enables	heparin binding	17588949	Function
1311	GO:0043394	IDA	enables	proteoglycan binding	29030641	Function
1311	GO:0043395	IDA	enables	heparan sulfate proteoglycan binding	17588949	Function

Component

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
1311	GO:0005576	HDA	located_in	extracellular region	27068509	Component
1311	GO:0005576	IDA	located_in	extracellular region	32747625	Component
1311	GO:0005615	HDA	located_in	extracellular space	20551380	Component
1311	GO:0062023	HDA	colocalizes_with	collagen-containing extracellular matrix	20551380	Component
1311	GO:0070062	HDA	located_in	extracellular exosome	23533145	Component

Process

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
1311	GO:0043066	IDA	involved_in	negative regulation of apoptotic process	17993464	Process
1311	GO:0051260	IDA	involved_in	protein homooligomerization	32747625	Process
1311	GO:0060173	IDA	involved_in	limb development	16542502	Process
1311	GO:1990079	IDA	involved_in	cartilage homeostasis	32747625	Process