Gene Ontology

Gene Info

  • Species:Mouse (Mus musculus)
  • GeneID:13489
  • Symbol:Drd2
  • Description:dopamine receptor D2

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
13489 GO:0001591 IDA enables dopamine neurotransmitter receptor activity, coupled via Gi/Go 1980140,7566118,8001143,8294904,8836575,11015197,12930822..... Function
13489 GO:0001591 IMP enables dopamine neurotransmitter receptor activity, coupled via Gi/Go 9140068,9247268,11069974,11172060,15721235 Function
13489 GO:0004930 IDA enables G protein-coupled receptor activity 14712229 Function
13489 GO:0004952 IDA enables dopamine neurotransmitter receptor activity 18671743 Function
13489 GO:0005515 IPI enables protein binding 25865831 Function
13489 GO:0035240 IDA enables dopamine binding 15716360 Function

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
13489 GO:0001659 IMP acts_upstream_of_or_within temperature homeostasis 10471093,18486343 Process
13489 GO:0001764 IMP acts_upstream_of neuron migration 17409246 Process
13489 GO:0001964 IMP NOT acts_upstream_of_or_within startle response 17324452 Process
13489 GO:0001964 IMP acts_upstream_of_or_within startle response 17712281 Process
13489 GO:0001975 IGI acts_upstream_of_or_within response to amphetamine 12097513 Process
13489 GO:0001975 IMP acts_upstream_of_or_within response to amphetamine 18486343 Process
13489 GO:0001976 IMP acts_upstream_of_or_within nervous system process involved in regulation of systemic arterial blood pressure 11566895 Process
13489 GO:0002027 IMP acts_upstream_of_or_within regulation of heart rate 11566895 Process
13489 GO:0002028 IMP acts_upstream_of_or_within regulation of sodium ion transport 11566895 Process
13489 GO:0002052 IDA acts_upstream_of_or_within positive regulation of neuroblast proliferation 17426594 Process
13489 GO:0007186 IDA acts_upstream_of_or_within G protein-coupled receptor signaling pathway 14712229 Process
13489 GO:0007195 IDA acts_upstream_of_or_within adenylate cyclase-inhibiting dopamine receptor signaling pathway 12665504 Process
13489 GO:0007195 IGI acts_upstream_of_or_within adenylate cyclase-inhibiting dopamine receptor signaling pathway 12223546 Process
13489 GO:0007212 IGI acts_upstream_of dopamine receptor signaling pathway 12097513 Process
13489 GO:0007270 IMP acts_upstream_of_or_within neuron-neuron synaptic transmission 12084937 Process
13489 GO:0007405 IDA acts_upstream_of neuroblast proliferation 17426594 Process
13489 GO:0007409 IMP acts_upstream_of_or_within axonogenesis 11438590 Process
13489 GO:0007608 IMP acts_upstream_of_or_within sensory perception of smell 16765459 Process
13489 GO:0007625 IMP acts_upstream_of_or_within grooming behavior 10698004 Process
13489 GO:0007626 IGI acts_upstream_of_or_within locomotory behavior 9354330,10908627,11150348,11172060,11864730,15272078,16280580..... Process
13489 GO:0007626 IMP acts_upstream_of_or_within locomotory behavior 9547254,10471093,10698004,11166059,11557166,12084937,12175868,..... Process
13489 GO:0007628 IMP acts_upstream_of_or_within adult walking behavior 7566118 Process
13489 GO:0007631 IGI acts_upstream_of_or_within feeding behavior 15272078 Process
13489 GO:0008104 IMP acts_upstream_of_or_within protein localization 10828532 Process
13489 GO:0008283 IGI acts_upstream_of cell population proliferation 9247268 Process
13489 GO:0008283 IMP acts_upstream_of cell population proliferation 9140068,9247267,9247268,9717839,10537166 Process
13489 GO:0008285 IGI acts_upstream_of_or_within negative regulation of cell population proliferation 9247268 Process
13489 GO:0008285 IMP acts_upstream_of_or_within negative regulation of cell population proliferation 9140068,9247267,9247268,9717839,10537166 Process
13489 GO:0008306 IMP acts_upstream_of_or_within associative learning 12084937,12182883,15061865 Process
13489 GO:0008542 IMP acts_upstream_of_or_within visual learning 12097513 Process
13489 GO:0009410 IDA acts_upstream_of_or_within response to xenobiotic stimulus 7549459 Process
13489 GO:0009410 IMP acts_upstream_of_or_within response to xenobiotic stimulus 16136297 Process
13489 GO:0009416 IMP acts_upstream_of_or_within response to light stimulus 16715079 Process
13489 GO:0016477 IMP acts_upstream_of cell migration 17409246 Process
13489 GO:0021853 IMP acts_upstream_of_or_within cerebral cortex GABAergic interneuron migration 17409246 Process
13489 GO:0021984 IMP acts_upstream_of_or_within adenohypophysis development 9140068 Process
13489 GO:0030432 IGI acts_upstream_of_or_within peristalsis 15272078 Process
13489 GO:0030432 IMP acts_upstream_of_or_within peristalsis 16525059 Process
13489 GO:0030534 IMP acts_upstream_of_or_within adult behavior 11303741 Process
13489 GO:0032228 IGI acts_upstream_of_or_within regulation of synaptic transmission, GABAergic 10934242 Process
13489 GO:0032228 IMP acts_upstream_of_or_within regulation of synaptic transmission, GABAergic 15080900 Process
13489 GO:0032922 IMP acts_upstream_of_or_within circadian regulation of gene expression 16606840 Process
13489 GO:0035810 IMP acts_upstream_of_or_within positive regulation of urine volume 11566895 Process
13489 GO:0035815 IMP acts_upstream_of_or_within positive regulation of renal sodium excretion 11566895 Process
13489 GO:0040018 IMP acts_upstream_of_or_within positive regulation of multicellular organism growth 11897683 Process
13489 GO:0042220 IDA acts_upstream_of_or_within response to cocaine 18671743 Process
13489 GO:0042220 IMP acts_upstream_of_or_within response to cocaine 11923462,12185400 Process
13489 GO:0042417 IMP acts_upstream_of_or_within dopamine metabolic process 7925842 Process
13489 GO:0043266 IMP acts_upstream_of_or_within regulation of potassium ion transport 11566895 Process
13489 GO:0043278 IMP acts_upstream_of_or_within response to morphine 9252189,11264672,11567069,12182883 Process
13489 GO:0043473 IMP acts_upstream_of_or_within pigmentation 9140068 Process
13489 GO:0043491 IMP acts_upstream_of protein kinase B signaling 17251429 Process
13489 GO:0045776 IMP acts_upstream_of_or_within negative regulation of blood pressure 11566895 Process
13489 GO:0045824 IMP involved_in negative regulation of innate immune response 23242137 Process
13489 GO:0048148 IMP acts_upstream_of_or_within behavioral response to cocaine 17426149 Process
13489 GO:0048149 IMP acts_upstream_of_or_within behavioral response to ethanol 11105945,11166059,12837020 Process
13489 GO:0048169 IMP acts_upstream_of_or_within regulation of long-term neuronal synaptic plasticity 9169514 Process
13489 GO:0048755 IMP acts_upstream_of_or_within branching morphogenesis of a nerve 11438590 Process
13489 GO:0050673 IGI acts_upstream_of epithelial cell proliferation 9247268 Process
13489 GO:0050673 IMP acts_upstream_of epithelial cell proliferation 9247268 Process
13489 GO:0050680 IGI acts_upstream_of_or_within negative regulation of epithelial cell proliferation 9247268 Process
13489 GO:0050680 IMP acts_upstream_of_or_within negative regulation of epithelial cell proliferation 9247268 Process
13489 GO:0050804 IMP acts_upstream_of_or_within modulation of chemical synaptic transmission 10974427 Process
13489 GO:0051580 EXP involved_in regulation of neurotransmitter uptake 12223553 Process
13489 GO:0051580 IDA involved_in regulation of neurotransmitter uptake 12223553 Process
13489 GO:0051580 IMP involved_in regulation of neurotransmitter uptake 12223553 Process
13489 GO:0051583 IMP acts_upstream_of dopamine uptake involved in synaptic transmission 9886065 Process
13489 GO:0051584 IMP acts_upstream_of_or_within regulation of dopamine uptake involved in synaptic transmission 12223553 Process
13489 GO:0051586 IMP acts_upstream_of_or_within positive regulation of dopamine uptake involved in synaptic transmission 9886065 Process
13489 GO:0051898 IMP acts_upstream_of_or_within negative regulation of protein kinase B signaling 17251429 Process
13489 GO:0051967 IMP acts_upstream_of_or_within negative regulation of synaptic transmission, glutamatergic 11160501 Process
13489 GO:0060124 IMP acts_upstream_of_or_within positive regulation of growth hormone secretion 11897683 Process
13489 GO:0060134 IMP NOT acts_upstream_of_or_within prepulse inhibition 17324452 Process
13489 GO:0060134 IMP acts_upstream_of_or_within prepulse inhibition 10341260,12417685,17712281 Process
13489 GO:0060158 IDA acts_upstream_of_or_within phospholipase C-activating dopamine receptor signaling pathway 15016423 Process
13489 GO:0060158 IGI acts_upstream_of_or_within phospholipase C-activating dopamine receptor signaling pathway 17194762 Process
13489 GO:0060160 IGI acts_upstream_of_or_within negative regulation of dopamine receptor signaling pathway 12097513 Process
13489 GO:0099171 EXP involved_in presynaptic modulation of chemical synaptic transmission 12223553,22586226 Process
13489 GO:0099171 IDA involved_in presynaptic modulation of chemical synaptic transmission 12223553,22586226 Process
13489 GO:0099171 IMP involved_in presynaptic modulation of chemical synaptic transmission 12223553 Process
13489 GO:1990384 IMP involved_in hyaloid vascular plexus regression 30936473 Process
13489 GO:2001223 IMP acts_upstream_of_or_within negative regulation of neuron migration 17409246 Process

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
13489 GO:0030424 IDA located_in axon 10051229 Component
13489 GO:0030425 IDA located_in dendrite 10051229 Component
13489 GO:0042734 IDA is_active_in presynaptic membrane 27035941 Component
13489 GO:0045211 IDA is_active_in postsynaptic membrane 27035941 Component
13489 GO:0098691 EXP is_active_in dopaminergic synapse 12223553 Component
13489 GO:0098691 IDA is_active_in dopaminergic synapse 12223553 Component
13489 GO:0098691 IMP is_active_in dopaminergic synapse 12223553 Component
13489 GO:0098978 IDA is_active_in glutamatergic synapse 27035941 Component
13489 GO:0098982 IDA is_active_in GABA-ergic synapse 27035941 Component