Gene Ontology

Gene Info

  • Species:Human (Homo sapiens)
  • GeneID:1399
  • Symbol:CRKL
  • Description:CRK like proto-oncogene, adaptor protein

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
1399 GO:0001784 IPI enables phosphotyrosine residue binding 20624904 Function
1399 GO:0003723 HDA enables RNA binding 22658674 Function
1399 GO:0005515 IPI enables protein binding 8626543,9546424,9788432,10022120,16273093,16284401,16443220,16..... Function
1399 GO:0042802 IPI enables identical protein binding 17161365,19168626 Function
1399 GO:0045296 HDA enables cadherin binding 25468996 Function
1399 GO:0061629 IDA enables RNA polymerase II-specific DNA-binding transcription factor binding 29581031 Function

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
1399 GO:0001933 IMP involved_in negative regulation of protein phosphorylation 23959425 Process
1399 GO:0001934 IMP involved_in positive regulation of protein phosphorylation 23959425 Process
1399 GO:0008284 IMP involved_in positive regulation of cell population proliferation 25540073 Process
1399 GO:0010629 IMP involved_in negative regulation of gene expression 23959425 Process
1399 GO:0070374 IMP involved_in positive regulation of ERK1 and ERK2 cascade 23959425 Process
1399 GO:0071560 IMP involved_in cellular response to transforming growth factor beta stimulus 23959425 Process
1399 GO:1900026 IMP involved_in positive regulation of substrate adhesion-dependent cell spreading 19004829 Process
1399 GO:1903977 IMP involved_in positive regulation of glial cell migration 23959425 Process

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
1399 GO:0005654 IDA located_in nucleoplasm Component
1399 GO:0005829 IDA located_in cytosol Component