Gene Ontology

Gene Info

  • Species:Mouse (Mus musculus)
  • GeneID:14083
  • Symbol:Ptk2
  • Description:PTK2 protein tyrosine kinase 2

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
14083 GO:0000226 IDA acts_upstream_of_or_within microtubule cytoskeleton organization 12941275 Process
14083 GO:0001525 IMP acts_upstream_of_or_within angiogenesis 15967814 Process
14083 GO:0001568 IMP acts_upstream_of_or_within blood vessel development 12595342,15967814 Process
14083 GO:0001570 IMP acts_upstream_of_or_within vasculogenesis 15967814 Process
14083 GO:0001764 IDA acts_upstream_of_or_within neuron migration 12941275 Process
14083 GO:0001764 IMP acts_upstream_of_or_within neuron migration 14642275 Process
14083 GO:0007097 IDA acts_upstream_of_or_within nuclear migration 12941275 Process
14083 GO:0007409 IMP acts_upstream_of axonogenesis 15378065 Process
14083 GO:0008284 IMP involved_in positive regulation of cell population proliferation 18206965 Process
14083 GO:0010507 IDA acts_upstream_of_or_within negative regulation of autophagy 27994061 Process
14083 GO:0010507 IMP acts_upstream_of_or_within negative regulation of autophagy 27994061 Process
14083 GO:0010613 IDA acts_upstream_of_or_within positive regulation of cardiac muscle hypertrophy 27994061 Process
14083 GO:0018108 IDA acts_upstream_of_or_within peptidyl-tyrosine phosphorylation 27994061 Process
14083 GO:0018108 IDA involved_in peptidyl-tyrosine phosphorylation 7529876 Process
14083 GO:0018108 IMP involved_in peptidyl-tyrosine phosphorylation 18297732 Process
14083 GO:0021955 IMP acts_upstream_of_or_within central nervous system neuron axonogenesis 15378065 Process
14083 GO:0030198 IMP acts_upstream_of_or_within extracellular matrix organization 14642275 Process
14083 GO:0035265 IGI acts_upstream_of organ growth 16374517 Process
14083 GO:0038083 IDA acts_upstream_of_or_within peptidyl-tyrosine autophosphorylation 27994061 Process
14083 GO:0043542 IMP acts_upstream_of_or_within endothelial cell migration 15967814 Process
14083 GO:0046621 IGI acts_upstream_of_or_within negative regulation of organ growth 16374517 Process
14083 GO:0046777 IDA involved_in protein autophosphorylation 7529876 Process
14083 GO:0046777 IMP acts_upstream_of_or_within protein autophosphorylation 2132399 Process
14083 GO:0050771 IMP acts_upstream_of_or_within negative regulation of axonogenesis 15378065 Process
14083 GO:0051964 IMP acts_upstream_of_or_within negative regulation of synapse assembly 15378065 Process
14083 GO:0071560 IDA acts_upstream_of_or_within cellular response to transforming growth factor beta stimulus 21829547 Process
14083 GO:1905274 IDA involved_in regulation of modification of postsynaptic actin cytoskeleton 19553453 Process
14083 GO:1905274 IMP involved_in regulation of modification of postsynaptic actin cytoskeleton 19553453 Process
14083 GO:2000060 IMP involved_in positive regulation of ubiquitin-dependent protein catabolic process 18206965 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
14083 GO:0004713 EXP enables protein tyrosine kinase activity 16298995,19553453 Function
14083 GO:0004713 IDA enables protein tyrosine kinase activity 7529876 Function
14083 GO:0004713 IMP enables protein tyrosine kinase activity 25059660 Function
14083 GO:0004715 IMP enables non-membrane spanning protein tyrosine kinase activity 18297732,27994061 Function
14083 GO:0005515 IPI enables protein binding 7479864,8816475,9148935,9418872,9461600,12674328,15138291,1629..... Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
14083 GO:0005634 IDA located_in nucleus 18206965 Component
14083 GO:0005925 IDA located_in focal adhesion 10699171,11784865,15728191,16405917,18297732 Component
14083 GO:0016324 IDA located_in apical plasma membrane 10742111 Component
14083 GO:0030027 IDA located_in lamellipodium 15728191 Component
14083 GO:0098978 IDA is_active_in glutamatergic synapse 19553453 Component
14083 GO:0098978 IMP is_active_in glutamatergic synapse 19553453 Component