Gene Ontology

Gene Info

  • Species:Rat (Rattus norvegicus)
  • GeneID:140908
  • Symbol:Cdk5
  • Description:cyclin-dependent kinase 5

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
140908 GO:0001934 IMP involved_in positive regulation of protein phosphorylation 28153522 Process
140908 GO:0006468 IDA acts_upstream_of_or_within protein phosphorylation 17202132 Process
140908 GO:0006468 IDA involved_in protein phosphorylation 8662984,15331630,15592431 Process
140908 GO:0006887 IMP involved_in exocytosis 15331630 Process
140908 GO:0006913 IMP involved_in nucleocytoplasmic transport 16887799 Process
140908 GO:0006974 IMP involved_in DNA damage response 19151707 Process
140908 GO:0007005 IMP involved_in mitochondrion organization 28153522 Process
140908 GO:0007519 IEP involved_in skeletal muscle tissue development 15208659 Process
140908 GO:0018105 IDA involved_in peptidyl-serine phosphorylation 12691662,14502288 Process
140908 GO:0030182 IDA involved_in neuron differentiation 8846918 Process
140908 GO:0030866 IMP involved_in cortical actin cytoskeleton organization 15331630 Process
140908 GO:0031175 IMP involved_in neuron projection development 8846918 Process
140908 GO:0034352 IMP involved_in positive regulation of glial cell apoptotic process 28153522 Process
140908 GO:0043525 IDA involved_in positive regulation of neuron apoptotic process 16192386 Process
140908 GO:0045055 IMP involved_in regulated exocytosis 15331630 Process
140908 GO:0046777 IDA involved_in protein autophosphorylation 15992363 Process
140908 GO:0048167 IMP involved_in regulation of synaptic plasticity 11675505,18498738 Process
140908 GO:0048488 IMP involved_in synaptic vesicle endocytosis 12855954 Process
140908 GO:0048812 IMP involved_in neuron projection morphogenesis 12535933 Process
140908 GO:0051402 IMP involved_in neuron apoptotic process 15592431 Process
140908 GO:0099509 IDA involved_in regulation of presynaptic cytosolic calcium ion concentration 23699505 Process
140908 GO:0099509 IMP involved_in regulation of presynaptic cytosolic calcium ion concentration 23699505 Process
140908 GO:0099533 IMP involved_in positive regulation of presynaptic cytosolic calcium concentration 23699505 Process
140908 GO:1901387 IMP involved_in positive regulation of voltage-gated calcium channel activity 23699505 Process
140908 GO:1904646 IDA involved_in cellular response to amyloid-beta 26224839 Process
140908 GO:1905806 EXP involved_in regulation of synapse pruning 17143272 Process
140908 GO:1905806 IDA involved_in regulation of synapse pruning 17143272 Process
140908 GO:1905806 IMP involved_in regulation of synapse pruning 17143272 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
140908 GO:0004672 IDA enables protein kinase activity 12084709,17202132 Function
140908 GO:0004674 IDA enables protein serine/threonine kinase activity 8662984,15994305 Function
140908 GO:0004693 IDA enables cyclin-dependent protein serine/threonine kinase activity 11675505,12691662,14502288,15286209,15331630,15471880,15592431..... Function
140908 GO:0005515 IPI enables protein binding 8846918,12963086,17036052,17341134,18498738 Function
140908 GO:0008092 IPI enables cytoskeletal protein binding 9313898 Function
140908 GO:0016301 IDA enables kinase activity 8846918 Function
140908 GO:0019901 IPI enables protein kinase binding 19700222 Function
140908 GO:0035173 IDA enables histone kinase activity 16407116 Function
140908 GO:0046875 IPI enables ephrin receptor binding 17143272 Function
140908 GO:0050321 IDA enables tau-protein kinase activity 15994305 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
140908 GO:0005634 IDA located_in nucleus 16192386 Component
140908 GO:0005737 IDA located_in cytoplasm 10683146,11276227,17491008 Component
140908 GO:0005874 IDA colocalizes_with microtubule 17491008 Component
140908 GO:0014069 IDA located_in postsynaptic density 17143272 Component
140908 GO:0016020 IDA located_in membrane 10683146,11276227 Component
140908 GO:0016533 IDA part_of protein kinase 5 complex 8662984 Component
140908 GO:0030424 IDA located_in axon 8846918 Component
140908 GO:0030425 IDA located_in dendrite 8846918,12223541 Component
140908 GO:0030426 IDA located_in growth cone 8846918,10683146 Component
140908 GO:0031594 IDA is_active_in neuromuscular junction 11276227 Component
140908 GO:0031594 IDA located_in neuromuscular junction 11276227 Component
140908 GO:0043005 IDA located_in neuron projection 10683146 Component
140908 GO:0043025 IDA located_in neuronal cell body 8846918 Component
140908 GO:0098685 EXP is_active_in Schaffer collateral - CA1 synapse 17143272 Component
140908 GO:0098685 IDA is_active_in Schaffer collateral - CA1 synapse 17143272 Component
140908 GO:0098685 IMP is_active_in Schaffer collateral - CA1 synapse 17143272 Component
140908 GO:0098793 IMP located_in presynapse 23699505 Component
140908 GO:0098794 IDA is_active_in postsynapse 11276227 Component
140908 GO:0098978 EXP is_active_in glutamatergic synapse 17143272 Component
140908 GO:0098978 IDA is_active_in glutamatergic synapse 17143272 Component
140908 GO:0098978 IMP is_active_in glutamatergic synapse 17143272 Component