Gene Ontology

Gene Info

• Species:Mouse (Mus musculus)
• GeneID:14118
• Symbol:Fbn1
• Description:fibrillin 1

Component

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
14118	GO:0001527	IDA	located_in	microfibril	26405179	Component
14118	GO:0005615	HDA	located_in	extracellular space	24006456	Component
14118	GO:0005615	IDA	is_active_in	extracellular space	29106398	Component
14118	GO:0062023	HDA	located_in	collagen-containing extracellular matrix	22159717,23658023,28071719	Component
14118	GO:0062023	IDA	located_in	collagen-containing extracellular matrix	17099216,24039232	Component

Function

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
14118	GO:0005179	IDA	enables	hormone activity	29106398,30997682,31230984,31798959,32337066	Function
14118	GO:0005515	IPI	enables	protein binding	19940141,25762570	Function

Process

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
14118	GO:0032100	IDA	involved_in	positive regulation of appetite	29106398	Process
14118	GO:0035582	IMP	involved_in	sequestering of BMP in extracellular matrix	20855508	Process
14118	GO:0035583	IMP	involved_in	sequestering of TGFbeta in extracellular matrix	20855508	Process
14118	GO:0045671	IDA	involved_in	negative regulation of osteoclast differentiation	24039232	Process
14118	GO:0046676	IDA	involved_in	negative regulation of insulin secretion	30997682	Process
14118	GO:1903444	IMP	involved_in	negative regulation of brown fat cell differentiation	33705351	Process
14118	GO:2001205	IDA	involved_in	negative regulation of osteoclast development	24039232	Process