Gene Ontology

Gene Info

  • Species:Mouse (Mus musculus)
  • GeneID:14370
  • Symbol:Fzd8
  • Description:frizzled class receptor 8

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
14370 GO:0001525 IDA acts_upstream_of_or_within angiogenesis 19129494 Process
14370 GO:0001934 IMP acts_upstream_of_or_within positive regulation of protein phosphorylation 15143170 Process
14370 GO:0016055 IDA acts_upstream_of_or_within Wnt signaling pathway 19129494 Process
14370 GO:0016055 IDA involved_in Wnt signaling pathway 11357136 Process
14370 GO:0033077 IMP acts_upstream_of_or_within T cell differentiation in thymus 11265645 Process
14370 GO:0043507 IDA acts_upstream_of_or_within positive regulation of JUN kinase activity 15195140 Process
14370 GO:0060070 IDA acts_upstream_of_or_within canonical Wnt signaling pathway 16543246 Process
14370 GO:0060070 IGI acts_upstream_of_or_within canonical Wnt signaling pathway 16115200 Process
14370 GO:0060070 IMP acts_upstream_of_or_within canonical Wnt signaling pathway 11265645,15064719,15143170 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
14370 GO:0005102 IPI enables signaling receptor binding 11029007 Function
14370 GO:0005515 IPI enables protein binding 11029007,11448771,11520064,15454084,15908424,16543246,18528331..... Function
14370 GO:0017147 IPI enables Wnt-protein binding 11357136,15454084,20093360,22653731 Function
14370 GO:0030165 IPI enables PDZ domain binding 11520064 Function
14370 GO:0042813 IPI enables Wnt receptor activity 15454084 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
14370 GO:0005886 IDA located_in plasma membrane 15035989 Component
14370 GO:0098992 EXP is_active_in neuronal dense core vesicle 21321602 Component
14370 GO:0098992 IDA is_active_in neuronal dense core vesicle 21321602 Component
14370 GO:1990851 IDA part_of Wnt-Frizzled-LRP5/6 complex 20093360 Component
14370 GO:1990851 IPI part_of Wnt-Frizzled-LRP5/6 complex 11029007,11448771 Component