Gene Ontology

Gene Info

• Species:Mouse (Mus musculus)
• GeneID:14468
• Symbol:Gbp2b
• Description:guanylate binding protein 2b

Process

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
14468	GO:0002218	IMP	involved_in	activation of innate immune response	24739961	Process
14468	GO:0035458	IDA	acts_upstream_of_or_within	cellular response to interferon-beta	19158679	Process
14468	GO:0042742	IMP	involved_in	defense response to bacterium	24715728,24739961	Process
14468	GO:0042832	IDA	acts_upstream_of_or_within	defense response to protozoan	18025219	Process
14468	GO:0044406	IDA	acts_upstream_of_or_within	adhesion of symbiont to host	18025219	Process
14468	GO:0050830	IDA	acts_upstream_of_or_within	defense response to Gram-positive bacterium	18025219	Process
14468	GO:0050830	IMP	acts_upstream_of_or_within	defense response to Gram-positive bacterium	21551061	Process
14468	GO:0051715	IMP	involved_in	cytolysis in another organism	24715728,24739961	Process
14468	GO:0071222	IMP	involved_in	cellular response to lipopolysaccharide	24715728	Process
14468	GO:0071346	IDA	acts_upstream_of_or_within	cellular response to type II interferon	18025219	Process
14468	GO:0140639	IMP	involved_in	positive regulation of pyroptosis	24715728	Process

Function

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
14468	GO:0003924	IMP	enables	GTPase activity	21551061	Function
14468	GO:0005515	IPI	enables	protein binding	21551061	Function
14468	GO:0019002	IDA	enables	GMP binding	3927587	Function

Component

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
14468	GO:0020005	IDA	located_in	symbiont-containing vacuole membrane	18025219	Component
14468	GO:0031410	IDA	located_in	cytoplasmic vesicle	18025219,21551061	Component