Gene Ontology

Gene Info

• Species:Human (Homo sapiens)
• GeneID:150
• Symbol:ADRA2A
• Description:adrenoceptor alpha 2A

Process

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
150	GO:0001819	IDA	involved_in	positive regulation of cytokine production	17655843	Process
150	GO:0007186	IDA	involved_in	G protein-coupled receptor signaling pathway	17215105,17655843	Process
150	GO:0030335	IMP	involved_in	positive regulation of cell migration	17655843	Process
150	GO:0032147	IDA	involved_in	activation of protein kinase activity	15653687	Process
150	GO:0032148	IDA	involved_in	activation of protein kinase B activity	17215105	Process
150	GO:0032870	IGI	involved_in	cellular response to hormone stimulus	10948198	Process
150	GO:0035624	IDA	involved_in	receptor transactivation	17215105,17655843	Process
150	GO:0042593	IMP	involved_in	glucose homeostasis	10952463	Process
150	GO:0043406	IDA	involved_in	positive regulation of MAP kinase activity	19477270	Process
150	GO:0043410	IDA	involved_in	positive regulation of MAPK cascade	10948191	Process
150	GO:0045741	IDA	involved_in	positive regulation of epidermal growth factor-activated receptor activity	17655843	Process
150	GO:0046676	IMP	involved_in	negative regulation of insulin secretion	10952463	Process
150	GO:0050995	IGI	involved_in	negative regulation of lipid catabolic process	10948198	Process
150	GO:0051044	IDA	involved_in	positive regulation of membrane protein ectodomain proteolysis	17655843	Process
150	GO:0061179	IMP	involved_in	negative regulation of insulin secretion involved in cellular response to glucose stimulus	19965390	Process
150	GO:0071875	IDA	involved_in	adrenergic receptor signaling pathway	10948191	Process
150	GO:0071881	IDA	involved_in	adenylate cyclase-inhibiting adrenergic receptor signaling pathway	10948191	Process
150	GO:0071882	IDA	involved_in	phospholipase C-activating adrenergic receptor signaling pathway	10948191	Process
150	GO:0090303	IMP	involved_in	positive regulation of wound healing	17655843	Process

Function

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
150	GO:0004938	IDA	enables	alpha2-adrenergic receptor activity	10948191	Function
150	GO:0005515	IPI	enables	protein binding	16531006	Function
150	GO:0019901	IPI	enables	protein kinase binding	15653687	Function
150	GO:0031696	IPI	enables	alpha-2C adrenergic receptor binding	16605244	Function
150	GO:0031996	IPI	enables	thioesterase binding	19477270	Function
150	GO:0032795	IDA	enables	heterotrimeric G-protein binding	10948191	Function
150	GO:0042803	IDA	enables	protein homodimerization activity	16605244	Function
150	GO:0046982	IPI	enables	protein heterodimerization activity	16605244	Function
150	GO:0051379	IDA	enables	epinephrine binding	2823383,10948191	Function
150	GO:0051380	IDA	enables	norepinephrine binding	2823383	Function

Component

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
150	GO:0005737	IDA	located_in	cytoplasm	19477270	Component
150	GO:0005886	IDA	located_in	plasma membrane	2823383,10948191,10948198	Component
150	GO:0043235	IDA	part_of	receptor complex	10948191	Component