Gene Ontology

Gene Info

  • Species:Mouse (Mus musculus)
  • GeneID:15182
  • Symbol:Hdac2
  • Description:histone deacetylase 2

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
15182 GO:0000122 IGI acts_upstream_of_or_within negative regulation of transcription by RNA polymerase II 10431247 Process
15182 GO:0000122 IGI involved_in negative regulation of transcription by RNA polymerase II 21093383 Process
15182 GO:0006476 IDA involved_in protein deacetylation 18754010 Process
15182 GO:0008284 IGI involved_in positive regulation of cell population proliferation 21093383 Process
15182 GO:0009913 IGI involved_in epidermal cell differentiation 21093383 Process
15182 GO:0010977 IDA involved_in negative regulation of neuron projection development 18754010 Process
15182 GO:0016358 IMP involved_in dendrite development 18754010 Process
15182 GO:0021766 IGI acts_upstream_of_or_within hippocampus development 19380719 Process
15182 GO:0030182 IGI acts_upstream_of_or_within neuron differentiation 19380719 Process
15182 GO:0032922 IDA involved_in circadian regulation of gene expression 15226430 Process
15182 GO:0035984 IDA acts_upstream_of_or_within cellular response to trichostatin A 24137001 Process
15182 GO:0042475 IGI involved_in odontogenesis of dentin-containing tooth 21093383 Process
15182 GO:0042733 IGI involved_in embryonic digit morphogenesis 21093383 Process
15182 GO:0043066 IGI involved_in negative regulation of apoptotic process 21093383 Process
15182 GO:0045892 IDA involved_in negative regulation of DNA-templated transcription 18754010 Process
15182 GO:0048709 IGI acts_upstream_of oligodendrocyte differentiation 19503085 Process
15182 GO:0048714 IGI acts_upstream_of_or_within positive regulation of oligodendrocyte differentiation 19503085 Process
15182 GO:0051091 IDA acts_upstream_of_or_within positive regulation of DNA-binding transcription factor activity 20833366 Process
15182 GO:0051896 IMP acts_upstream_of_or_within regulation of protein kinase B signaling 17322895 Process
15182 GO:0055013 IMP acts_upstream_of_or_within cardiac muscle cell development 17322895 Process
15182 GO:0060038 IMP acts_upstream_of cardiac muscle cell proliferation 17322895 Process
15182 GO:0060044 IMP acts_upstream_of_or_within negative regulation of cardiac muscle cell proliferation 17322895 Process
15182 GO:0060297 IMP acts_upstream_of_or_within regulation of sarcomere organization 17322895 Process
15182 GO:0060789 IGI involved_in hair follicle placode formation 21093383 Process
15182 GO:0061029 IGI involved_in eyelid development in camera-type eye 21093383 Process
15182 GO:0061198 IGI involved_in fungiform papilla formation 21093383 Process
15182 GO:0090090 IGI acts_upstream_of_or_within negative regulation of canonical Wnt signaling pathway 19503085 Process
15182 GO:0090311 IGI acts_upstream_of_or_within regulation of protein deacetylation 20833366 Process
15182 GO:1902894 IGI involved_in negative regulation of miRNA transcription 24675724 Process
15182 GO:1902894 IMP involved_in negative regulation of miRNA transcription 24675724 Process
15182 GO:2001243 IGI acts_upstream_of_or_within negative regulation of intrinsic apoptotic signaling pathway 21093383 Process

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
15182 GO:0000785 IDA part_of chromatin 12007404,18754010 Component
15182 GO:0000792 IDA part_of heterochromatin 14519686,14643676 Component
15182 GO:0005634 IDA located_in nucleus 20720167,22770845,28053041 Component
15182 GO:0005657 IDA located_in replication fork 10888872 Component
15182 GO:0005667 IPI part_of transcription regulator complex 17182846 Component
15182 GO:0017053 IPI part_of transcription repressor complex 17182846 Component
15182 GO:0090571 IDA part_of RNA polymerase II transcription repressor complex 12007404 Component

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
15182 GO:0000978 IDA enables RNA polymerase II cis-regulatory region sequence-specific DNA binding 24137001,28053041 Function
15182 GO:0001222 IPI enables transcription corepressor binding 12007404 Function
15182 GO:0003682 IDA enables chromatin binding 17392792,18754010 Function
15182 GO:0004407 IDA enables histone deacetylase activity 12975471,15226430,18754010,30279482 Function
15182 GO:0004407 IGI enables histone deacetylase activity 12975471 Function
15182 GO:0005515 IPI enables protein binding 10888872,11101889,11836251,11923873,12975471,15226430,15696166..... Function
15182 GO:0019899 IPI enables enzyme binding 20972425 Function
15182 GO:0031490 IDA enables chromatin DNA binding 18458156 Function
15182 GO:0033558 IDA enables protein lysine deacetylase activity 18754010 Function
15182 GO:0034739 IMP enables histone H4K16 deacetylase activity 23516383 Function
15182 GO:0035851 IPI enables Krueppel-associated box domain binding 21177534,22391310 Function
15182 GO:0140297 IPI enables DNA-binding transcription factor binding 33795231 Function
15182 GO:0160009 IDA enables histone decrotonylase activity 30279482 Function