Gene Ontology

Gene Info

• Species:Mouse (Mus musculus)
• GeneID:15467
• Symbol:Eif2ak1
• Description:eukaryotic translation initiation factor 2 alpha kinase 1

Process

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
15467	GO:0002526	IMP	acts_upstream_of_or_within	acute inflammatory response	17932563	Process
15467	GO:0006417	IMP	acts_upstream_of_or_within	regulation of translation	11726526	Process
15467	GO:0006909	IMP	acts_upstream_of_or_within	phagocytosis	17932563	Process
15467	GO:0008285	IDA	involved_in	negative regulation of cell population proliferation	11050009	Process
15467	GO:0010999	IGI	acts_upstream_of_or_within	regulation of eIF2 alpha phosphorylation by heme	15931390	Process
15467	GO:0030225	IMP	acts_upstream_of_or_within	macrophage differentiation	17932563	Process
15467	GO:0046501	IGI	acts_upstream_of_or_within	protoporphyrinogen IX metabolic process	15931390	Process
15467	GO:0046777	IEP	involved_in	protein autophosphorylation	11560503	Process
15467	GO:0046984	IGI	acts_upstream_of_or_within	regulation of hemoglobin biosynthetic process	15931390	Process
15467	GO:0046986	IDA	involved_in	negative regulation of hemoglobin biosynthetic process	11050009	Process
15467	GO:0051649	IMP	acts_upstream_of_or_within	establishment of localization in cell	17932563	Process
15467	GO:0060586	IMP	acts_upstream_of_or_within	multicellular organismal-level iron ion homeostasis	17932563	Process

Function

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
15467	GO:0004672	IMP	enables	protein kinase activity	11726526	Function
15467	GO:0005515	IPI	enables	protein binding	21223507	Function
15467	GO:0020037	IDA	enables	heme binding	10671563	Function
15467	GO:0042803	IPI	enables	protein homodimerization activity	11560503	Function

Component

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
15467	GO:0005737	IDA	located_in	cytoplasm	11050009,17932563	Component