Gene Ontology

Gene Info

  • Species:Human (Homo sapiens)
  • GeneID:1639
  • Symbol:DCTN1
  • Description:dynactin subunit 1

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
1639 GO:0000132 IMP involved_in establishment of mitotic spindle orientation 22327364 Process
1639 GO:0007528 IMP involved_in neuromuscular junction development 18305234 Process
1639 GO:0010457 IMP involved_in centriole-centriole cohesion 23386061 Process
1639 GO:0021517 IMP involved_in ventral spinal cord development 18305234 Process
1639 GO:0031116 IDA involved_in positive regulation of microtubule polymerization 23874158 Process
1639 GO:0031116 IMP involved_in positive regulation of microtubule polymerization 16505168 Process
1639 GO:0034454 IMP involved_in microtubule anchoring at centrosome 23386061 Process
1639 GO:0042147 IMP involved_in retrograde transport, endosome to Golgi 19619496 Process
1639 GO:0050905 IMP involved_in neuromuscular process 18305234 Process
1639 GO:0051081 IMP involved_in nuclear membrane disassembly 20679239 Process
1639 GO:0060236 IMP involved_in regulation of mitotic spindle organization 23027904 Process
1639 GO:0061744 IMP involved_in motor behavior 18305234,18364389 Process
1639 GO:0070050 IMP involved_in neuron cellular homeostasis 18305234 Process
1639 GO:0090063 IDA involved_in positive regulation of microtubule nucleation 23874158 Process
1639 GO:0098930 IMP NOT involved_in axonal transport 18364389 Process
1639 GO:1904398 IMP involved_in positive regulation of neuromuscular junction development 18364389 Process
1639 GO:1905515 IMP involved_in non-motile cilium assembly 25774020 Process
1639 GO:1990535 IMP involved_in neuron projection maintenance 18305234,18364389 Process

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
1639 GO:0000776 IDA located_in kinetochore 19468067,23027904 Component
1639 GO:0000922 IDA located_in spindle pole 14718566 Component
1639 GO:0005635 IDA located_in nuclear envelope 20679239 Component
1639 GO:0005737 IDA located_in cytoplasm 18305234 Component
1639 GO:0005813 IDA located_in centrosome 20719959,21399614,23985322,25774020 Component
1639 GO:0005814 IDA located_in centriole 23213374,23386061,25774020 Component
1639 GO:0005819 IDA located_in spindle 25774020 Component
1639 GO:0005874 IDA located_in microtubule 21525035,22777741,25774020 Component
1639 GO:0005875 IMP part_of microtubule associated complex 16505168 Component
1639 GO:0005938 IDA colocalizes_with cell cortex 23509069 Component
1639 GO:0005938 IDA located_in cell cortex 23027904 Component
1639 GO:0015630 IDA located_in microtubule cytoskeleton Component
1639 GO:0016020 HDA located_in membrane 19946888 Component
1639 GO:0035371 IDA located_in microtubule plus-end 26972003 Component
1639 GO:0043005 IDA located_in neuron projection 18364389 Component
1639 GO:0043025 IDA located_in neuronal cell body 18364389 Component
1639 GO:0045171 IDA located_in intercellular bridge Component
1639 GO:0072686 IDA located_in mitotic spindle Component
1639 GO:0099738 IDA located_in cell cortex region 22327364 Component
1639 GO:0120103 IDA part_of centriolar subdistal appendage 23213374 Component

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
1639 GO:0005515 IPI enables protein binding 9361024,9722614,12857853,15107855,17139249,17532294,17828275,1..... Function
1639 GO:0008017 IDA enables microtubule binding 23874158,26972003 Function
1639 GO:0008017 IMP enables microtubule binding 16505168 Function
1639 GO:0015631 IDA enables tubulin binding 23874158 Function
1639 GO:0019901 IPI enables protein kinase binding 17139249 Function