Gene Ontology

Gene Info

• Species:Mouse (Mus musculus)
• GeneID:16428
• Symbol:Itk
• Description:IL2 inducible T cell kinase

Process

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
16428	GO:0001819	IMP	involved_in	positive regulation of cytokine production	10213685	Process
16428	GO:0001865	IGI	acts_upstream_of_or_within	NK T cell differentiation	18292523	Process
16428	GO:0001865	IMP	acts_upstream_of_or_within	NK T cell differentiation	18292523	Process
16428	GO:0002250	IMP	involved_in	adaptive immune response	10213685	Process
16428	GO:0006468	IMP	involved_in	protein phosphorylation	15662016	Process
16428	GO:0007202	IMP	involved_in	activation of phospholipase C activity	10213685	Process
16428	GO:0032609	IGI	acts_upstream_of_or_within	type II interferon production	18292523	Process
16428	GO:0032609	IMP	acts_upstream_of_or_within	type II interferon production	18292523	Process
16428	GO:0032633	IGI	acts_upstream_of_or_within	interleukin-4 production	18292523	Process
16428	GO:0032633	IMP	acts_upstream_of_or_within	interleukin-4 production	18292523	Process
16428	GO:0046629	IMP	involved_in	gamma-delta T cell activation	23562159	Process
16428	GO:0050852	IMP	involved_in	T cell receptor signaling pathway	10213685	Process

Function

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
16428	GO:0005515	IPI	enables	protein binding	15662016,19597499,19955438	Function

Component

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
16428	GO:0005634	IDA	located_in	nucleus	15662016	Component
16428	GO:0005911	IDA	located_in	cell-cell junction	23793062	Component