Gene Ontology

Gene Info

  • Species:Mouse (Mus musculus)
  • GeneID:16768
  • Symbol:Lag3
  • Description:lymphocyte-activation gene 3

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
16768 GO:0002270 IMP involved_in plasmacytoid dendritic cell activation 19201841 Process
16768 GO:0007166 IDA acts_upstream_of_or_within cell surface receptor signaling pathway 12421911 Process
16768 GO:0007166 IDA involved_in cell surface receptor signaling pathway 12209638,30580966 Process
16768 GO:0032623 IDA acts_upstream_of interleukin-2 production 12421911 Process
16768 GO:0032703 IDA acts_upstream_of_or_within negative regulation of interleukin-2 production 12421911 Process
16768 GO:0042110 IDA acts_upstream_of T cell activation 12421911 Process
16768 GO:0042267 IDA acts_upstream_of natural killer cell mediated cytotoxicity 8602528 Process
16768 GO:0042267 IMP acts_upstream_of natural killer cell mediated cytotoxicity 8602528 Process
16768 GO:0045590 IMP involved_in negative regulation of regulatory T cell differentiation 15485628 Process
16768 GO:0045954 IDA acts_upstream_of_or_within positive regulation of natural killer cell mediated cytotoxicity 8602528 Process
16768 GO:0045954 IMP acts_upstream_of_or_within positive regulation of natural killer cell mediated cytotoxicity 8602528 Process
16768 GO:0050776 IDA involved_in regulation of immune response 30580966 Process
16768 GO:0050868 IDA acts_upstream_of_or_within negative regulation of T cell activation 12421911 Process
16768 GO:0050868 IDA involved_in negative regulation of T cell activation 12209638,30580966 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
16768 GO:0004888 IDA enables transmembrane signaling receptor activity 12209638,12421911,30580966 Function
16768 GO:0005515 IPI enables protein binding 30580966 Function
16768 GO:0042289 IDA enables MHC class II protein binding 12209638,12421911 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
16768 GO:0005576 IDA located_in extracellular region 17245433,30580966 Component
16768 GO:0009897 IDA located_in external side of plasma membrane 8602528,12421911 Component