Gene Ontology

Gene Info

  • Species:Mouse (Mus musculus)
  • GeneID:16870
  • Symbol:Lhx2
  • Description:LIM homeobox protein 2

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
16870 GO:0000978 IDA enables RNA polymerase II cis-regulatory region sequence-specific DNA binding 15173589 Function
16870 GO:0000978 IMP enables RNA polymerase II cis-regulatory region sequence-specific DNA binding 7513049,28053041 Function
16870 GO:0001228 IDA enables DNA-binding transcription activator activity, RNA polymerase II-specific 7513049 Function
16870 GO:0001228 IMP enables DNA-binding transcription activator activity, RNA polymerase II-specific 7513049,26371318 Function
16870 GO:0003682 IDA enables chromatin binding 19146846,24012369 Function
16870 GO:0005515 IPI enables protein binding 9697309,10431247,10593900,20599664,24643061,28053041..... Function
16870 GO:0008134 IPI enables transcription factor binding 17991461 Function
16870 GO:0043565 IDA enables sequence-specific DNA binding 15173589 Function

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
16870 GO:0001843 IMP acts_upstream_of_or_within neural tube closure 11719201 Process
16870 GO:0001942 IMP acts_upstream_of_or_within hair follicle development 24012369 Process
16870 GO:0007399 IMP acts_upstream_of_or_within nervous system development 9247336 Process
16870 GO:0007411 IMP acts_upstream_of_or_within axon guidance 17493606 Process
16870 GO:0007411 IMP involved_in axon guidance 22457488 Process
16870 GO:0007420 IMP acts_upstream_of_or_within brain development 14566948,15295034 Process
16870 GO:0007498 IMP acts_upstream_of_or_within mesoderm development 9247336 Process
16870 GO:0009953 IMP acts_upstream_of_or_within dorsal/ventral pattern formation 11165475,14566948 Process
16870 GO:0021537 IMP acts_upstream_of_or_within telencephalon development 11165475,11719201,17493606,19820705 Process
16870 GO:0021772 IMP acts_upstream_of_or_within olfactory bulb development 19820705 Process
16870 GO:0021978 IGI acts_upstream_of_or_within telencephalon regionalization 11719201 Process
16870 GO:0021978 IMP acts_upstream_of_or_within telencephalon regionalization 11719201 Process
16870 GO:0021987 IMP acts_upstream_of_or_within cerebral cortex development 19820705 Process
16870 GO:0021987 IMP involved_in cerebral cortex development 26371318,28053041 Process
16870 GO:0022008 IDA acts_upstream_of_or_within neurogenesis 18184563 Process
16870 GO:0030182 IMP acts_upstream_of_or_within neuron differentiation 15173589 Process
16870 GO:0045199 IMP acts_upstream_of_or_within maintenance of epithelial cell apical/basal polarity 24012369 Process
16870 GO:0045814 IMP involved_in negative regulation of gene expression, epigenetic 28053041 Process
16870 GO:0045893 IDA involved_in positive regulation of DNA-templated transcription 10593900 Process
16870 GO:0045893 IMP involved_in positive regulation of DNA-templated transcription 22734700 Process
16870 GO:0045944 IDA acts_upstream_of_or_within positive regulation of transcription by RNA polymerase II 24012369 Process
16870 GO:0045944 IDA involved_in positive regulation of transcription by RNA polymerase II 7513049,19146846 Process
16870 GO:0045944 IGI acts_upstream_of_or_within positive regulation of transcription by RNA polymerase II 10431247,19146846 Process
16870 GO:0045944 IMP involved_in positive regulation of transcription by RNA polymerase II 26371318 Process
16870 GO:0048646 IMP acts_upstream_of_or_within anatomical structure formation involved in morphogenesis 11719201 Process
16870 GO:0048675 IDA acts_upstream_of_or_within axon extension 21857657 Process
16870 GO:0050768 IMP involved_in negative regulation of neurogenesis 26371318,28053041 Process
16870 GO:0060041 IGI acts_upstream_of_or_within retina development in camera-type eye 19146846 Process
16870 GO:2000179 IMP involved_in positive regulation of neural precursor cell proliferation 26371318 Process
16870 GO:2000678 IGI acts_upstream_of_or_within negative regulation of transcription regulatory region DNA binding 9697309 Process

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
16870 GO:0005622 IDA located_in intracellular anatomical structure 10482234 Component
16870 GO:0005634 IDA located_in nucleus 18076286,24012369 Component
16870 GO:0005634 IMP located_in nucleus 26371318,28053041 Component