Gene Ontology

Gene Info

  • Species:Mouse (Mus musculus)
  • GeneID:16975
  • Symbol:Lrp8
  • Description:low density lipoprotein receptor-related protein 8, apolipoprotein e receptor

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
16975 GO:0001540 IPI enables amyloid-beta binding 16227578 Function
16975 GO:0005515 IPI enables protein binding 10571240,10571241,12573468,16227578,16332682,20223219..... Function
16975 GO:0034185 IDA enables apolipoprotein binding 10571240 Function
16975 GO:0038025 IMP enables reelin receptor activity 18778775 Function
16975 GO:0048306 IPI enables calcium-dependent protein binding 10571240 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
16975 GO:0005615 IDA located_in extracellular space 15950758 Component
16975 GO:0009986 IDA located_in cell surface 16227578 Component

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
16975 GO:0007268 IMP involved_in chemical synaptic transmission 18778775 Process
16975 GO:0021517 IEP involved_in ventral spinal cord development 20711475 Process
16975 GO:0021541 IMP involved_in ammon gyrus development 18778775 Process
16975 GO:0021766 IGI acts_upstream_of_or_within hippocampus development 17330141 Process
16975 GO:0021819 IGI acts_upstream_of_or_within layer formation in cerebral cortex 17330141 Process
16975 GO:0032793 IMP involved_in positive regulation of CREB transcription factor activity 21852430 Process
16975 GO:0038026 IMP involved_in reelin-mediated signaling pathway 18778775,21852430 Process
16975 GO:0042981 IMP involved_in regulation of apoptotic process 29336888 Process
16975 GO:0045088 IMP involved_in regulation of innate immune response 29336888 Process
16975 GO:0045860 IGI acts_upstream_of_or_within positive regulation of protein kinase activity 12526740 Process
16975 GO:0048813 IMP involved_in dendrite morphogenesis 18778775 Process
16975 GO:0050731 IMP involved_in positive regulation of peptidyl-tyrosine phosphorylation 21852430 Process
16975 GO:0050804 IMP involved_in modulation of chemical synaptic transmission 18778775 Process
16975 GO:0061003 IMP involved_in positive regulation of dendritic spine morphogenesis 21852430 Process
16975 GO:0061098 IMP involved_in positive regulation of protein tyrosine kinase activity 21852430 Process
16975 GO:1900006 IGI involved_in positive regulation of dendrite development 18778775 Process