Gene Ontology

Gene Info

  • Species:Mouse (Mus musculus)
  • GeneID:17125
  • Symbol:Smad1
  • Description:SMAD family member 1

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
17125 GO:0000165 IMP acts_upstream_of_or_within MAPK cascade 15198985 Process
17125 GO:0001649 IDA involved_in osteoblast differentiation 7798324 Process
17125 GO:0001657 IEP involved_in ureteric bud development 14656760 Process
17125 GO:0001710 IGI acts_upstream_of_or_within mesodermal cell fate commitment 16801560 Process
17125 GO:0002051 IGI acts_upstream_of_or_within osteoblast fate commitment 15150273 Process
17125 GO:0006357 IDA acts_upstream_of_or_within regulation of transcription by RNA polymerase II 12270938,14633973 Process
17125 GO:0006366 IDA acts_upstream_of transcription by RNA polymerase II 18997172 Process
17125 GO:0006468 IDA acts_upstream_of_or_within protein phosphorylation 18776146 Process
17125 GO:0006954 IEP involved_in inflammatory response 12151307 Process
17125 GO:0007276 IMP acts_upstream_of_or_within gamete generation 15198985 Process
17125 GO:0008283 IMP acts_upstream_of cell population proliferation 15899870 Process
17125 GO:0008285 IMP acts_upstream_of_or_within negative regulation of cell population proliferation 15899870 Process
17125 GO:0010628 IMP acts_upstream_of_or_within positive regulation of gene expression 18622394 Process
17125 GO:0030509 IDA acts_upstream_of_or_within BMP signaling pathway 25100727 Process
17125 GO:0030509 IDA involved_in BMP signaling pathway 21976273 Process
17125 GO:0030509 IGI acts_upstream_of_or_within BMP signaling pathway 16604073,19224984 Process
17125 GO:0030509 IGI involved_in BMP signaling pathway 19252488,20843790 Process
17125 GO:0030509 IMP acts_upstream_of_or_within BMP signaling pathway 15198985 Process
17125 GO:0030901 IMP acts_upstream_of_or_within midbrain development 15899870 Process
17125 GO:0030902 IMP acts_upstream_of_or_within hindbrain development 15899870 Process
17125 GO:0042592 IMP acts_upstream_of_or_within homeostatic process 15198985 Process
17125 GO:0045669 IGI acts_upstream_of_or_within positive regulation of osteoblast differentiation 15150273 Process
17125 GO:0045944 IDA acts_upstream_of_or_within positive regulation of transcription by RNA polymerase II 15557274,16556916,18997172,19251704 Process
17125 GO:0045944 IGI acts_upstream_of_or_within positive regulation of transcription by RNA polymerase II 24211589 Process
17125 GO:0051148 IDA involved_in negative regulation of muscle cell differentiation 21976273 Process
17125 GO:0051216 IGI acts_upstream_of_or_within cartilage development 19224984 Process
17125 GO:0060038 IGI acts_upstream_of_or_within cardiac muscle cell proliferation 17350578 Process
17125 GO:0060038 IMP acts_upstream_of_or_within cardiac muscle cell proliferation 17350578 Process
17125 GO:0060348 IGI acts_upstream_of_or_within bone development 19224984 Process
17125 GO:0060395 IGI involved_in SMAD protein signal transduction 19252488 Process
17125 GO:0061036 IDA acts_upstream_of_or_within positive regulation of cartilage development 19251704 Process
17125 GO:0071407 IDA acts_upstream_of_or_within cellular response to organic cyclic compound 19103752 Process
17125 GO:0071773 IGI involved_in cellular response to BMP stimulus 20843790 Process
17125 GO:1901522 IGI involved_in positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus 20843790 Process
17125 GO:1902895 IMP involved_in positive regulation of miRNA transcription 21145505 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
17125 GO:0000978 IDA enables RNA polymerase II cis-regulatory region sequence-specific DNA binding 18692037 Function
17125 GO:0000981 IDA enables DNA-binding transcription factor activity, RNA polymerase II-specific 21976273 Function
17125 GO:0003700 IDA enables DNA-binding transcription factor activity 14633973,16556916 Function
17125 GO:0005515 IPI enables protein binding 12370310,14633973,15150273,15542835,16511561,19416967,19536134..... Function
17125 GO:0042802 IPI enables identical protein binding 21724602 Function
17125 GO:0043565 IDA enables sequence-specific DNA binding 23169531 Function
17125 GO:0070878 IDA enables primary miRNA binding 21145505 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
17125 GO:0005634 IDA is_active_in nucleus 21976273 Component
17125 GO:0005634 IDA located_in nucleus 12151307,19103752,19252488,19793887,19796622,25100727..... Component
17125 GO:0005667 IDA part_of transcription regulator complex 14633973 Component
17125 GO:0005737 IDA located_in cytoplasm 11160896,19103752,19252488 Component
17125 GO:0071142 IPI part_of homomeric SMAD protein complex 20147459 Component