Gene Ontology

Gene Info

• Species:Worm (Caenorhabditis elegans)
• GeneID:174305
• Symbol:ire-1
• Description:Endoribonuclease;Serine/threonine-protein kinase

Process

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
174305	GO:0001666	IMP	involved_in	response to hypoxia	20733002	Process
174305	GO:0002119	IGI	involved_in	nematode larval development	11779465	Process
174305	GO:0006990	IGI	involved_in	positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response	18216284	Process
174305	GO:0006990	IMP	involved_in	positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response	18216284	Process
174305	GO:0030968	IGI	involved_in	endoplasmic reticulum unfolded protein response	11779465	Process
174305	GO:0030968	IMP	involved_in	endoplasmic reticulum unfolded protein response	11779465,11780124,25340700	Process
174305	GO:0034976	IMP	involved_in	response to endoplasmic reticulum stress	20733002	Process
174305	GO:0035966	IGI	involved_in	response to topologically incorrect protein	23335331	Process
174305	GO:0035966	IMP	involved_in	response to topologically incorrect protein	23335331	Process
174305	GO:0036498	IMP	acts_upstream_of_positive_effect	IRE1-mediated unfolded protein response	11780124	Process
174305	GO:0036498	IMP	involved_in	IRE1-mediated unfolded protein response	11779465	Process
174305	GO:0051093	IMP	acts_upstream_of_positive_effect	negative regulation of developmental process	11780124	Process
174305	GO:0072332	EXP	acts_upstream_of_positive_effect	intrinsic apoptotic signaling pathway by p53 class mediator	25340700	Process
174305	GO:1990440	IMP	involved_in	positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress	19822669	Process

Function

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
174305	GO:0004521	IMP	enables	RNA endonuclease activity	11779465	Function

Component

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
174305	GO:0043025	IMP	located_in	neuronal cell body	23791175	Component