Gene Ontology

Gene Info

• Species:Worm (Caenorhabditis elegans)
• GeneID:175502
• Symbol:tir-1
• Description:ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase;NAD(+) hydrolase tir-1;Sterile alpha and TIR motif-containing protein tir-1

Function

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
175502	GO:0003953	IDA	enables	NAD+ nucleosidase activity	31439792,34184985	Function
175502	GO:0005515	IPI	enables	protein binding	15625192	Function
175502	GO:0019901	IPI	enables	protein kinase binding	15625192	Function
175502	GO:0031267	IPI	enables	small GTPase binding	15625192	Function
175502	GO:0035591	IDA	enables	signaling adaptor activity	15625192	Function
175502	GO:0042802	IPI	enables	identical protein binding	14704431,19123269	Function
175502	GO:0043539	IDA	enables	protein serine/threonine kinase activator activity	15625192	Function
175502	GO:0140537	IDA	enables	transcription regulator activator activity	15625192	Function

Component

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
175502	GO:0005737	IDA	located_in	cytoplasm	15625192	Component
175502	GO:0030424	IDA	located_in	axon	23505381	Component
175502	GO:0044297	IDA	located_in	cell body	23505381	Component
175502	GO:1904115	IDA	located_in	axon cytoplasm	15625192	Component

Process

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
175502	GO:0008104	IMP	involved_in	protein localization	15625192	Process
175502	GO:0010628	IMP	involved_in	positive regulation of gene expression	17526726	Process
175502	GO:0010629	IMP	involved_in	negative regulation of gene expression	17526726	Process
175502	GO:0019677	IDA	involved_in	NAD catabolic process	27671644,31439792,34184985	Process
175502	GO:0042427	IMP	acts_upstream_of_or_within	serotonin biosynthetic process	23505381	Process
175502	GO:0042742	IMP	involved_in	defense response to bacterium	15048112	Process
175502	GO:0045168	IMP	involved_in	cell-cell signaling involved in cell fate commitment	15625192	Process
175502	GO:0045944	IMP	involved_in	positive regulation of transcription by RNA polymerase II	17888400	Process
175502	GO:0048678	IMP	involved_in	response to axon injury	34184985	Process
175502	GO:0050829	IMP	involved_in	defense response to Gram-negative bacterium	23505381	Process
175502	GO:0050832	IMP	involved_in	defense response to fungus	15048112,18394898	Process
175502	GO:0140367	IMP	involved_in	antibacterial innate immune response	19837372	Process
175502	GO:1901216	IDA	involved_in	positive regulation of neuron death	27671644	Process
175502	GO:1902097	IMP	involved_in	positive regulation of transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacterium	17888400	Process