Gene Ontology

Gene Info

  • Species:Human (Homo sapiens)
  • GeneID:1763
  • Symbol:DNA2
  • Description:DNA replication helicase/nuclease 2

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
1763 GO:0000076 IMP involved_in DNA replication checkpoint signaling 22570476 Process
1763 GO:0000729 IDA involved_in DNA double-strand break processing 21325134 Process
1763 GO:0006260 IMP involved_in DNA replication 22570476 Process
1763 GO:0006264 IDA involved_in mitochondrial DNA replication 18995831,19487465 Process
1763 GO:0006284 IDA involved_in base-excision repair 18995831 Process
1763 GO:0033567 IDA involved_in DNA replication, Okazaki fragment processing 22570407 Process
1763 GO:0043137 IDA involved_in DNA replication, removal of RNA primer 18995831 Process
1763 GO:0043504 IDA involved_in mitochondrial DNA repair 19487465 Process
1763 GO:0045740 IDA involved_in positive regulation of DNA replication 18995831 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
1763 GO:0003677 IDA enables DNA binding 20019387,22570407 Function
1763 GO:0003678 IDA NOT enables DNA helicase activity 16595799 Function
1763 GO:0003678 IDA enables DNA helicase activity 16595800 Function
1763 GO:0004518 IDA enables nuclease activity 21325134 Function
1763 GO:0005515 IPI enables protein binding 20019387,21325134 Function
1763 GO:0016890 IDA enables site-specific endodeoxyribonuclease activity, specific for altered base 18995831 Function
1763 GO:0017108 IDA enables 5'-flap endonuclease activity 16595799,16595800,18995831,20019387,22570407 Function
1763 GO:0017116 IDA enables single-stranded DNA helicase activity 16595799,16595800 Function
1763 GO:0043139 IDA enables 5'-3' DNA helicase activity 20019387 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
1763 GO:0005634 IDA located_in nucleus 19487465 Component
1763 GO:0005654 IDA located_in nucleoplasm Component
1763 GO:0005739 IDA located_in mitochondrion Component
1763 GO:0042645 IDA located_in mitochondrial nucleoid 19487465 Component