Gene Ontology

Gene Info

  • Species:Human (Homo sapiens)
  • GeneID:177
  • Symbol:AGER
  • Description:advanced glycosylation end-product specific receptor

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
177 GO:0001540 IDA enables amyloid-beta binding 29518356 Function
177 GO:0001540 IPI enables amyloid-beta binding 22406537,23973487 Function
177 GO:0005515 IPI enables protein binding 16061848,16716307,16954185,17474147,17660747,17726019,18922799..... Function
177 GO:0038023 IMP enables signaling receptor activity 15457210 Function
177 GO:0042802 IPI enables identical protein binding 24119142 Function
177 GO:0044548 IPI enables S100 protein binding 15033494 Function
177 GO:0044877 IPI enables protein-containing complex binding 29518356 Function
177 GO:0060090 EXP enables molecular adaptor activity 22194616 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
177 GO:0001650 IDA located_in fibrillar center Component
177 GO:0005886 IDA located_in plasma membrane Component
177 GO:0016324 IDA located_in apical plasma membrane 26005850 Component
177 GO:0030054 IDA located_in cell junction Component

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
177 GO:0001774 IGI involved_in microglial cell activation 15457210 Process
177 GO:0001914 IDA involved_in regulation of T cell mediated cytotoxicity 22473704 Process
177 GO:0001934 IGI involved_in positive regulation of protein phosphorylation 15457210 Process
177 GO:0007611 IGI involved_in learning or memory 15457210 Process
177 GO:0010255 IDA involved_in glucose mediated signaling pathway 25689357 Process
177 GO:0031175 IGI involved_in neuron projection development 10391939 Process
177 GO:0032693 IDA involved_in negative regulation of interleukin-10 production 22473704 Process
177 GO:0032735 IMP involved_in positive regulation of interleukin-12 production 15944249 Process
177 GO:0034116 IGI involved_in positive regulation of heterotypic cell-cell adhesion 11078691 Process
177 GO:0042104 IMP involved_in positive regulation of activated T cell proliferation 15944249 Process
177 GO:0046330 IGI involved_in positive regulation of JNK cascade 20739563 Process
177 GO:0048143 IGI involved_in astrocyte activation 15457210 Process
177 GO:0051092 IDA involved_in positive regulation of NF-kappaB transcription factor activity 10391939 Process
177 GO:0051092 IGI involved_in positive regulation of NF-kappaB transcription factor activity 15457210 Process
177 GO:0070374 IGI involved_in positive regulation of ERK1 and ERK2 cascade 15457210 Process
177 GO:0150003 IGI involved_in regulation of spontaneous synaptic transmission 15457210 Process
177 GO:0150104 IDA involved_in transport across blood-brain barrier 23973487 Process
177 GO:1900272 IGI involved_in negative regulation of long-term synaptic potentiation 15457210 Process
177 GO:1900453 IGI involved_in negative regulation of long-term synaptic depression 20739563 Process
177 GO:1900745 IGI involved_in positive regulation of p38MAPK cascade 20739563 Process
177 GO:1901224 IGI involved_in positive regulation of NIK/NF-kappaB signaling 15457210 Process
177 GO:1902961 IGI involved_in positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process 22406537 Process
177 GO:2000439 IMP involved_in positive regulation of monocyte extravasation 11078691 Process
177 GO:2000514 IDA involved_in regulation of CD4-positive, alpha-beta T cell activation 22473704 Process
177 GO:2001200 IMP involved_in positive regulation of dendritic cell differentiation 15944249 Process