Gene Ontology

Gene Info

  • Species:Mouse (Mus musculus)
  • GeneID:17973
  • Symbol:Nck1
  • Description:non-catalytic region of tyrosine kinase adaptor protein 1

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
17973 GO:0005515 IPI enables protein binding 14580336,15148308,16777958,20697350 Function
17973 GO:0019904 IPI enables protein domain specific binding 8438166 Function
17973 GO:0046875 IPI enables ephrin receptor binding 19505147 Function
17973 GO:0071074 IPI enables eukaryotic initiation factor eIF2 binding 11959995 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
17973 GO:0005911 IDA located_in cell-cell junction 23793062 Component
17973 GO:0012506 IDA located_in vesicle membrane 12147689 Component

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
17973 GO:0006930 IGI acts_upstream_of_or_within substrate-dependent cell migration, cell extension 19414610 Process
17973 GO:0007015 IMP acts_upstream_of_or_within actin filament organization 12637565 Process
17973 GO:0010976 IMP acts_upstream_of_or_within positive regulation of neuron projection development 19505147 Process
17973 GO:0016477 IMP acts_upstream_of_or_within cell migration 12637565 Process
17973 GO:0030032 IMP acts_upstream_of_or_within lamellipodium assembly 12808099 Process
17973 GO:0030334 IGI acts_upstream_of_or_within regulation of cell migration 19505147 Process
17973 GO:0030838 IGI acts_upstream_of_or_within positive regulation of actin filament polymerization 17923684 Process
17973 GO:0036493 IGI involved_in positive regulation of translation in response to endoplasmic reticulum stress 14676213 Process
17973 GO:0048013 IMP acts_upstream_of_or_within ephrin receptor signaling pathway 19505147 Process
17973 GO:0051707 IMP acts_upstream_of_or_within response to other organism 22966049 Process
17973 GO:1902237 IGI involved_in positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway 16835242 Process
17973 GO:1903898 IGI involved_in negative regulation of PERK-mediated unfolded protein response 14676213 Process
17973 GO:1903912 IGI involved_in negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation 14676213,16835242 Process
17973 GO:1990441 IGI involved_in negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress 16835242 Process