Gene Ontology

Gene Info

  • Species:Worm (Caenorhabditis elegans)
  • GeneID:179959
  • Symbol:hda-1
  • Description:Histone deacetylase 1

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
179959 GO:0000118 IPI part_of histone deacetylase complex 9875852 Component
179959 GO:0000785 IDA part_of chromatin 32934238 Component
179959 GO:0005634 IDA located_in nucleus 11940660,32934238 Component
179959 GO:0005634 IMP located_in nucleus 32789178 Component
179959 GO:0005737 IDA located_in cytoplasm 11940660,32934238 Component
179959 GO:0016581 IMP part_of NuRD complex 32789178 Component
179959 GO:0016581 IPI part_of NuRD complex 12507426 Component
179959 GO:0043073 IDA located_in germ cell nucleus 11940660 Component

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
179959 GO:0000122 IMP involved_in negative regulation of transcription by RNA polymerase II 11742996,11940660,23437011 Process
179959 GO:0006325 IMP acts_upstream_of_or_within chromatin organization 32789178 Process
179959 GO:0008340 IMP acts_upstream_of_or_within determination of adult lifespan 32934238 Process
179959 GO:0008406 IMP involved_in gonad development 11940660 Process
179959 GO:0009792 IMP involved_in embryo development ending in birth or egg hatching 9531533,9875852 Process
179959 GO:0016575 IDA involved_in histone deacetylation 12507426 Process
179959 GO:0030154 IMP involved_in cell differentiation 26506306 Process
179959 GO:0030334 IMP involved_in regulation of cell migration 26506306 Process
179959 GO:0034514 IMP acts_upstream_of_or_within mitochondrial unfolded protein response 32789178,32934238 Process
179959 GO:0040027 IGI involved_in negative regulation of vulval development 9875852,10704416 Process
179959 GO:0040027 IMP involved_in negative regulation of vulval development 11940660 Process
179959 GO:0042001 IMP involved_in hermaphrodite somatic sex determination 17011494 Process
179959 GO:0045088 IMP involved_in regulation of innate immune response 32934238 Process
179959 GO:0045138 IMP involved_in nematode male tail tip morphogenesis 17506990 Process
179959 GO:0045595 IGI involved_in regulation of cell differentiation 9531533 Process
179959 GO:0045746 IMP involved_in negative regulation of Notch signaling pathway 11940660 Process
179959 GO:0045944 IMP involved_in positive regulation of transcription by RNA polymerase II 23229554 Process
179959 GO:0046580 IGI involved_in negative regulation of Ras protein signal transduction 9875852,10704416 Process
179959 GO:0048557 IGI involved_in embryonic digestive tract morphogenesis 15196946 Process
179959 GO:1903854 IGI involved_in negative regulation of stress response to copper ion 23437011 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
179959 GO:0003714 IPI contributes_to transcription corepressor activity 11742996 Function
179959 GO:0004407 IDA enables histone deacetylase activity 12507426 Function
179959 GO:0005515 IPI enables protein binding 9875852,11742996,12507426,17011494,23437011,32934238..... Function
179959 GO:0061629 IPI enables RNA polymerase II-specific DNA-binding transcription factor binding 23437011 Function