Gene Ontology

Gene Info

  • Species:Mouse (Mus musculus)
  • GeneID:17999
  • Symbol:Nedd4
  • Description:neural precursor cell expressed, developmentally down-regulated 4

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
17999 GO:0000122 IMP acts_upstream_of_or_within negative regulation of transcription by RNA polymerase II 20026598 Process
17999 GO:0002250 IMP acts_upstream_of_or_within adaptive immune response 18931680 Process
17999 GO:0003151 IGI acts_upstream_of_or_within outflow tract morphogenesis 20026598 Process
17999 GO:0003151 IMP acts_upstream_of_or_within outflow tract morphogenesis 20026598 Process
17999 GO:0003197 IGI acts_upstream_of_or_within endocardial cushion development 20026598 Process
17999 GO:0003197 IMP acts_upstream_of_or_within endocardial cushion development 20026598 Process
17999 GO:0006511 IMP acts_upstream_of_or_within ubiquitin-dependent protein catabolic process 18931680 Process
17999 GO:0006513 IDA acts_upstream_of_or_within protein monoubiquitination 21920314 Process
17999 GO:0006814 IDA acts_upstream_of sodium ion transport 10212229 Process
17999 GO:0007528 IMP acts_upstream_of_or_within neuromuscular junction development 19345204 Process
17999 GO:0010766 IDA acts_upstream_of_or_within negative regulation of sodium ion transport 10212229 Process
17999 GO:0016567 IDA acts_upstream_of_or_within protein ubiquitination 9182527 Process
17999 GO:0030948 IDA involved_in negative regulation of vascular endothelial growth factor receptor signaling pathway 15060076 Process
17999 GO:0042110 IMP acts_upstream_of_or_within T cell activation 18931680 Process
17999 GO:0045732 IDA acts_upstream_of_or_within positive regulation of protein catabolic process 11748237 Process
17999 GO:0048514 IGI acts_upstream_of_or_within blood vessel morphogenesis 20026598 Process
17999 GO:0048514 IMP acts_upstream_of_or_within blood vessel morphogenesis 20026598 Process
17999 GO:0048814 IMP involved_in regulation of dendrite morphogenesis 20159449 Process
17999 GO:0050807 IMP acts_upstream_of_or_within regulation of synapse organization 19345204 Process
17999 GO:0051649 IDA acts_upstream_of establishment of localization in cell 10212229 Process

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
17999 GO:0000151 IPI part_of ubiquitin ligase complex 11042109 Component
17999 GO:0005737 IDA located_in cytoplasm 14973438 Component
17999 GO:0005829 IDA located_in cytosol 9182527,19794060 Component
17999 GO:0016020 IDA located_in membrane 14973438 Component
17999 GO:0043197 IDA located_in dendritic spine 25505317 Component
17999 GO:0098978 IDA is_active_in glutamatergic synapse 25505317 Component
17999 GO:0098978 IMP is_active_in glutamatergic synapse 25505317 Component
17999 GO:0099524 IDA is_active_in postsynaptic cytosol 25505317 Component
17999 GO:0099524 IMP is_active_in postsynaptic cytosol 25505317 Component

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
17999 GO:0005515 IPI enables protein binding 10446181,11042109,11717310,15060076,17544362,20159449,21920314..... Function
17999 GO:0019871 IDA enables sodium channel inhibitor activity 10212229 Function
17999 GO:0035255 IDA enables ionotropic glutamate receptor binding 25505317 Function
17999 GO:0050815 IDA enables phosphoserine residue binding 10037602 Function
17999 GO:0050816 IDA enables phosphothreonine residue binding 10037602 Function
17999 GO:0061630 IDA enables ubiquitin protein ligase activity 9182527,11717310 Function
17999 GO:0070064 IPI enables proline-rich region binding 9305852,11748237 Function