Gene Ontology

Gene Info

  • Species:Mouse (Mus musculus)
  • GeneID:18016
  • Symbol:Nf2
  • Description:neurofibromin 2

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
18016 GO:0000165 IMP acts_upstream_of MAPK cascade 16405865 Process
18016 GO:0001707 IMP acts_upstream_of_or_within mesoderm formation 9171370 Process
18016 GO:0006469 IDA acts_upstream_of_or_within negative regulation of protein kinase activity 14580336 Process
18016 GO:0006469 IMP acts_upstream_of_or_within negative regulation of protein kinase activity 16405865 Process
18016 GO:0007398 IMP acts_upstream_of_or_within ectoderm development 9171370 Process
18016 GO:0007420 IMP acts_upstream_of_or_within brain development 23863479 Process
18016 GO:0008285 IMP acts_upstream_of_or_within negative regulation of cell population proliferation 9553042 Process
18016 GO:0010626 IMP acts_upstream_of_or_within negative regulation of Schwann cell proliferation 10887156 Process
18016 GO:0014010 IMP acts_upstream_of Schwann cell proliferation 10887156 Process
18016 GO:0014013 IMP acts_upstream_of_or_within regulation of gliogenesis 25433207 Process
18016 GO:0021766 IMP acts_upstream_of_or_within hippocampus development 23863479 Process
18016 GO:0031647 IMP acts_upstream_of_or_within regulation of protein stability 23863479 Process
18016 GO:0033687 IMP acts_upstream_of osteoblast proliferation 10887156 Process
18016 GO:0033689 IMP acts_upstream_of_or_within negative regulation of osteoblast proliferation 10887156 Process
18016 GO:0042127 IMP acts_upstream_of_or_within regulation of cell population proliferation 12695331 Process
18016 GO:0042475 IMP acts_upstream_of_or_within odontogenesis of dentin-containing tooth 10887156 Process
18016 GO:0043409 IMP acts_upstream_of_or_within negative regulation of MAPK cascade 16405865 Process
18016 GO:0045216 IMP acts_upstream_of_or_within cell-cell junction organization 12695331 Process
18016 GO:0045597 IMP acts_upstream_of_or_within positive regulation of cell differentiation 23863479 Process
18016 GO:0050767 IMP acts_upstream_of_or_within regulation of neurogenesis 25433207 Process
18016 GO:0070306 IMP involved_in lens fiber cell differentiation 20181838 Process
18016 GO:0072091 IGI acts_upstream_of_or_within regulation of stem cell proliferation 25433207 Process
18016 GO:0072091 IMP acts_upstream_of_or_within regulation of stem cell proliferation 25433207 Process
18016 GO:1900180 IMP acts_upstream_of_or_within regulation of protein localization to nucleus 23863479 Process
18016 GO:2000177 IMP acts_upstream_of_or_within regulation of neural precursor cell proliferation 23863479 Process

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
18016 GO:0001726 IDA located_in ruffle 9563848 Component
18016 GO:0005634 IDA located_in nucleus 15133494 Component
18016 GO:0005737 IDA located_in cytoplasm 8547603,15133494 Component
18016 GO:0005856 IDA located_in cytoskeleton 15467741 Component
18016 GO:0005912 IMP located_in adherens junction 12695331 Component
18016 GO:0030027 IDA located_in lamellipodium 9563848 Component
18016 GO:0030175 IDA located_in filopodium 9563848 Component
18016 GO:0030864 IDA located_in cortical actin cytoskeleton 15467741 Component
18016 GO:0032154 IDA located_in cleavage furrow 9631655 Component
18016 GO:0043005 IDA located_in neuron projection 25433207 Component
18016 GO:0044297 IDA located_in cell body 25433207 Component
18016 GO:0045177 IDA located_in apical part of cell 23863479 Component

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
18016 GO:0005515 IPI enables protein binding 12695331,14580336,16405865,25026211 Function