Gene Ontology

Gene Info

  • Species:Mouse (Mus musculus)
  • GeneID:18479
  • Symbol:Pak1
  • Description:p21 (RAC1) activated kinase 1

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
18479 GO:0004672 IDA enables protein kinase activity 14580336,23509247,23528453 Function
18479 GO:0004674 IDA enables protein serine/threonine kinase activity 28408623 Function
18479 GO:0005515 IPI enables protein binding 10967094,12123608,18541910,18716323,21828338,22751929..... Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
18479 GO:0005634 IDA located_in nucleus 12950086 Component
18479 GO:0005737 IDA located_in cytoplasm 12213441,12950086 Component
18479 GO:0014069 IDA is_active_in postsynaptic density 15182717 Component
18479 GO:0014069 IDA located_in postsynaptic density 17114649 Component
18479 GO:0014069 IEP is_active_in postsynaptic density 15182717 Component
18479 GO:0030424 IDA located_in axon 12950086 Component
18479 GO:0030425 IDA located_in dendrite 22022532 Component
18479 GO:0030426 IDA located_in growth cone 11604394 Component
18479 GO:0098978 IDA is_active_in glutamatergic synapse 15182717 Component
18479 GO:0098978 IEP is_active_in glutamatergic synapse 15182717 Component
18479 GO:0098982 EXP is_active_in GABA-ergic synapse 27296803 Component
18479 GO:0098982 IDA is_active_in GABA-ergic synapse 27296803 Component
18479 GO:0098982 IEP is_active_in GABA-ergic synapse 27296803 Component
18479 GO:0098982 IMP is_active_in GABA-ergic synapse 27296803 Component

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
18479 GO:0007528 IGI acts_upstream_of_or_within neuromuscular junction development 12165471 Process
18479 GO:0010468 IGI acts_upstream_of_or_within regulation of gene expression 25242307 Process
18479 GO:0016358 IDA acts_upstream_of_or_within dendrite development 12213441 Process
18479 GO:0019226 IGI acts_upstream_of_or_within transmission of nerve impulse 27583434 Process
18479 GO:0021764 IGI acts_upstream_of_or_within amygdala development 25242307 Process
18479 GO:0043113 IGI acts_upstream_of_or_within receptor clustering 12165471 Process
18479 GO:0043408 IGI acts_upstream_of_or_within regulation of MAPK cascade 25242307 Process
18479 GO:0060996 IGI acts_upstream_of_or_within dendritic spine development 23509247 Process
18479 GO:0061534 IGI acts_upstream_of_or_within gamma-aminobutyric acid secretion, neurotransmission 25242307 Process
18479 GO:0061535 IGI acts_upstream_of_or_within glutamate secretion, neurotransmission 25242307 Process
18479 GO:0071407 IDA acts_upstream_of_or_within cellular response to organic cyclic compound 23509247 Process
18479 GO:0098597 IGI acts_upstream_of_or_within observational learning 25242307 Process
18479 GO:0150036 EXP involved_in regulation of trans-synaptic signaling by endocannabinoid, modulating synaptic transmission 27296803 Process
18479 GO:0150036 IDA involved_in regulation of trans-synaptic signaling by endocannabinoid, modulating synaptic transmission 27296803 Process
18479 GO:0150036 IEP involved_in regulation of trans-synaptic signaling by endocannabinoid, modulating synaptic transmission 27296803 Process
18479 GO:0150036 IMP involved_in regulation of trans-synaptic signaling by endocannabinoid, modulating synaptic transmission 27296803 Process
18479 GO:1900271 IGI acts_upstream_of_or_within regulation of long-term synaptic potentiation 25242307 Process