Gene Ontology

Gene Info

  • Species:Mouse (Mus musculus)
  • GeneID:18596
  • Symbol:Pdgfrb
  • Description:platelet derived growth factor receptor, beta polypeptide

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
18596 GO:0001568 IEP involved_in blood vessel development 10375497 Process
18596 GO:0001701 IMP acts_upstream_of_or_within in utero embryonic development 17143286 Process
18596 GO:0001822 IMP acts_upstream_of_or_within kidney development 17143286 Process
18596 GO:0001894 IMP acts_upstream_of_or_within tissue homeostasis 17143286 Process
18596 GO:0006807 IMP acts_upstream_of_or_within nitrogen compound metabolic process 17143286 Process
18596 GO:0007165 IDA acts_upstream_of_or_within signal transduction 11940581 Process
18596 GO:0014068 IDA involved_in positive regulation of phosphatidylinositol 3-kinase signaling 17942966 Process
18596 GO:0014911 IGI involved_in positive regulation of smooth muscle cell migration 19742316 Process
18596 GO:0014911 IMP involved_in positive regulation of smooth muscle cell migration 10375497 Process
18596 GO:0018108 IDA involved_in peptidyl-tyrosine phosphorylation 14624252 Process
18596 GO:0030097 IMP NOT involved_in hemopoiesis 11264163 Process
18596 GO:0030325 IGI acts_upstream_of_or_within adrenal gland development 19056881 Process
18596 GO:0032956 IGI involved_in regulation of actin cytoskeleton organization 19742316 Process
18596 GO:0035441 IMP involved_in cell migration involved in vasculogenesis 14624252 Process
18596 GO:0035793 IMP involved_in positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway 19019919 Process
18596 GO:0035909 IGI involved_in aorta morphogenesis 19742316 Process
18596 GO:0043406 IDA involved_in positive regulation of MAP kinase activity 17942966 Process
18596 GO:0045840 IDA involved_in positive regulation of mitotic nuclear division 17942966 Process
18596 GO:0046777 IDA involved_in protein autophosphorylation 14624252 Process
18596 GO:0048008 IMP acts_upstream_of_or_within platelet-derived growth factor receptor signaling pathway 17143286 Process
18596 GO:0048008 IPI acts_upstream_of_or_within platelet-derived growth factor receptor signaling pathway 26437238 Process
18596 GO:0048568 IEP involved_in embryonic organ development 10375497 Process
18596 GO:0048661 IMP involved_in positive regulation of smooth muscle cell proliferation 10375497 Process
18596 GO:0048705 IMP acts_upstream_of_or_within skeletal system morphogenesis 17143286 Process
18596 GO:0048745 IMP acts_upstream_of_or_within smooth muscle tissue development 17143286 Process
18596 GO:0050730 IMP acts_upstream_of_or_within regulation of peptidyl-tyrosine phosphorylation 11940581 Process
18596 GO:0050921 IDA involved_in positive regulation of chemotaxis 19019919 Process
18596 GO:0055003 IGI involved_in cardiac myofibril assembly 11239463 Process
18596 GO:0060981 IMP involved_in cell migration involved in coronary angiogenesis 14624252 Process
18596 GO:0061298 IGI involved_in retina vasculature development in camera-type eye 11239463 Process
18596 GO:0061298 IMP involved_in retina vasculature development in camera-type eye 14624252 Process
18596 GO:0070301 IMP acts_upstream_of_or_within cellular response to hydrogen peroxide 23651497 Process
18596 GO:0070374 IDA involved_in positive regulation of ERK1 and ERK2 cascade 17942966 Process
18596 GO:0070374 IMP involved_in positive regulation of ERK1 and ERK2 cascade 14624252 Process
18596 GO:0071670 IGI involved_in smooth muscle cell chemotaxis 19742316 Process
18596 GO:0072223 IEP involved_in metanephric glomerular mesangium development 9693135 Process
18596 GO:0072262 IMP involved_in metanephric glomerular mesangial cell proliferation involved in metanephros development 9693135 Process
18596 GO:0072277 IGI involved_in metanephric glomerular capillary formation 11239463 Process
18596 GO:0090280 IMP involved_in positive regulation of calcium ion import 19019919 Process
18596 GO:0097178 IDA acts_upstream_of_or_within ruffle assembly 26437238 Process
18596 GO:0106096 IMP acts_upstream_of_or_within response to ceramide 23651497 Process
18596 GO:2000379 IMP involved_in positive regulation of reactive oxygen species metabolic process 19019919 Process
18596 GO:2000573 IMP involved_in positive regulation of DNA biosynthetic process 19019919 Process

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
18596 GO:0001726 IDA located_in ruffle 26437238 Component
18596 GO:0005737 IDA located_in cytoplasm 22027834,24029230 Component
18596 GO:0009986 IDA located_in cell surface 24029230 Component

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
18596 GO:0005017 IDA enables platelet-derived growth factor receptor activity 26437238 Function
18596 GO:0005102 IPI enables signaling receptor binding 16456542 Function
18596 GO:0005515 IPI enables protein binding 7730365,10644978,12614164,16456542,17609376,18515860,21427700..... Function
18596 GO:0016301 IMP enables kinase activity 12808090 Function