Gene Ontology

Gene Info

  • Species:Mouse (Mus musculus)
  • GeneID:18754
  • Symbol:Prkce
  • Description:protein kinase C, epsilon

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
18754 GO:0000165 IDA acts_upstream_of MAPK cascade 11884367 Process
18754 GO:0002281 IMP acts_upstream_of_or_within macrophage activation involved in immune response 11696589 Process
18754 GO:0006468 IDA acts_upstream_of_or_within protein phosphorylation 12551921 Process
18754 GO:0010763 IMP involved_in positive regulation of fibroblast migration 16270034 Process
18754 GO:0010811 IGI acts_upstream_of_or_within positive regulation of cell-substrate adhesion 15949469 Process
18754 GO:0010811 IMP acts_upstream_of_or_within positive regulation of cell-substrate adhesion 15949469 Process
18754 GO:0019216 IMP acts_upstream_of_or_within regulation of lipid metabolic process 19401415 Process
18754 GO:0030073 IMP acts_upstream_of insulin secretion 12837755 Process
18754 GO:0030838 IDA involved_in positive regulation of actin filament polymerization 11746497 Process
18754 GO:0031397 IMP involved_in negative regulation of protein ubiquitination 25470454 Process
18754 GO:0031589 IGI acts_upstream_of cell-substrate adhesion 15949469 Process
18754 GO:0031589 IMP acts_upstream_of cell-substrate adhesion 15949469 Process
18754 GO:0031663 IMP acts_upstream_of_or_within lipopolysaccharide-mediated signaling pathway 11696589 Process
18754 GO:0031663 IMP involved_in lipopolysaccharide-mediated signaling pathway 16757566 Process
18754 GO:0032024 IMP acts_upstream_of_or_within positive regulation of insulin secretion 12837755 Process
18754 GO:0032230 IMP acts_upstream_of_or_within positive regulation of synaptic transmission, GABAergic 17875639 Process
18754 GO:0035641 IGI acts_upstream_of_or_within locomotory exploration behavior 17908177 Process
18754 GO:0035669 IMP involved_in TRAM-dependent toll-like receptor 4 signaling pathway 16757566 Process
18754 GO:0043123 IMP acts_upstream_of_or_within positive regulation of I-kappaB kinase/NF-kappaB signaling 11696589 Process
18754 GO:0043278 IMP acts_upstream_of_or_within response to morphine 16899053 Process
18754 GO:0043410 IDA acts_upstream_of_or_within positive regulation of MAPK cascade 11884367 Process
18754 GO:0043410 IMP acts_upstream_of_or_within positive regulation of MAPK cascade 11696589 Process
18754 GO:0050730 IMP acts_upstream_of_or_within regulation of peptidyl-tyrosine phosphorylation 11940581 Process
18754 GO:0050996 IMP acts_upstream_of_or_within positive regulation of lipid catabolic process 19401415 Process
18754 GO:0051279 IDA acts_upstream_of_or_within regulation of release of sequestered calcium ion into cytosol 23479225 Process
18754 GO:0051279 IMP acts_upstream_of_or_within regulation of release of sequestered calcium ion into cytosol 15905535 Process
18754 GO:0051649 IMP acts_upstream_of establishment of localization in cell 12837755,17728398 Process
18754 GO:0051932 IMP acts_upstream_of synaptic transmission, GABAergic 17875639 Process
18754 GO:0061178 IMP acts_upstream_of_or_within regulation of insulin secretion involved in cellular response to glucose stimulus 19401415 Process
18754 GO:0070254 IMP acts_upstream_of mucus secretion 17728398 Process
18754 GO:0070257 IMP acts_upstream_of_or_within positive regulation of mucus secretion 17728398 Process
18754 GO:0071361 IGI acts_upstream_of_or_within cellular response to ethanol 17875639 Process
18754 GO:0071380 IDA acts_upstream_of_or_within cellular response to prostaglandin E stimulus 23479225 Process
18754 GO:0071456 IDA acts_upstream_of_or_within cellular response to hypoxia 18070622 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
18754 GO:0003785 IDA enables actin monomer binding 11746497 Function
18754 GO:0004674 IDA enables protein serine/threonine kinase activity 17875639 Function
18754 GO:0004699 IDA enables calcium-independent protein kinase C activity 10879655 Function
18754 GO:0005515 IPI enables protein binding 11139474,18237277,18604201,19429675,20338032 Function
18754 GO:0030546 IDA enables signaling receptor activator activity 17875639 Function
18754 GO:0035276 IDA enables ethanol binding 19432558 Function
18754 GO:0071889 IPI enables 14-3-3 protein binding 18604201 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
18754 GO:0005634 IDA located_in nucleus 14613966 Component
18754 GO:0005737 IDA located_in cytoplasm 14613966 Component
18754 GO:0005739 IDA located_in mitochondrion 11884367 Component
18754 GO:0005794 IDA colocalizes_with Golgi apparatus 17611075 Component
18754 GO:0005829 IDA located_in cytosol 11884367 Component
18754 GO:0016020 IDA located_in membrane 16270034,18323529 Component
18754 GO:0048471 IDA located_in perinuclear region of cytoplasm 17611075 Component
18754 GO:0071944 IDA located_in cell periphery 17611075 Component