Gene Ontology

Gene Info

  • Species:Mouse (Mus musculus)
  • GeneID:19106
  • Symbol:Eif2ak2
  • Description:eukaryotic translation initiation factor 2-alpha kinase 2

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
19106 GO:0001819 IMP involved_in positive regulation of cytokine production 20038207 Process
19106 GO:0006412 IDA acts_upstream_of_or_within translation 7519779 Process
19106 GO:0006468 IDA acts_upstream_of_or_within protein phosphorylation 7519779,15542627 Process
19106 GO:0030968 IDA acts_upstream_of_or_within endoplasmic reticulum unfolded protein response 15542627 Process
19106 GO:0032722 IMP involved_in positive regulation of chemokine production 20038207 Process
19106 GO:0032874 IMP involved_in positive regulation of stress-activated MAPK cascade 20038207 Process
19106 GO:0043066 IGI acts_upstream_of_or_within negative regulation of apoptotic process 15542627 Process
19106 GO:0045071 IMP involved_in negative regulation of viral genome replication 20038207 Process
19106 GO:0046777 IDA acts_upstream_of_or_within protein autophosphorylation 7519779,15542627 Process
19106 GO:0046777 IDA involved_in protein autophosphorylation 22801494 Process
19106 GO:1900225 IMP involved_in regulation of NLRP3 inflammasome complex assembly 22801494 Process
19106 GO:1901224 IMP involved_in positive regulation of NIK/NF-kappaB signaling 20038207 Process
19106 GO:1901532 IMP involved_in regulation of hematopoietic progenitor cell differentiation 23403623 Process
19106 GO:1902033 IMP involved_in regulation of hematopoietic stem cell proliferation 23403623 Process
19106 GO:1902036 IMP involved_in regulation of hematopoietic stem cell differentiation 23403623 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
19106 GO:0003725 IDA enables double-stranded RNA binding 21703541 Function
19106 GO:0004672 IDA enables protein kinase activity 7519779,15545996 Function
19106 GO:0004672 IMP enables protein kinase activity 21123651 Function
19106 GO:0005515 IPI enables protein binding 7519779,10488071,12882984,18362360,20144759,22801494..... Function