Gene Ontology

Gene Info

  • Species:Mouse (Mus musculus)
  • GeneID:19261
  • Symbol:Sirpa
  • Description:signal-regulatory protein alpha

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
19261 GO:0001933 IMP involved_in negative regulation of protein phosphorylation 17954568 Process
19261 GO:0002244 IMP acts_upstream_of_or_within hematopoietic progenitor cell differentiation 24029230 Process
19261 GO:0006910 IDA acts_upstream_of_or_within phagocytosis, recognition 14634079 Process
19261 GO:0006911 IDA acts_upstream_of_or_within phagocytosis, engulfment 14634079 Process
19261 GO:0007010 IMP acts_upstream_of_or_within cytoskeleton organization 11118207 Process
19261 GO:0007015 IMP acts_upstream_of_or_within actin filament organization 11118207 Process
19261 GO:0007160 IMP acts_upstream_of_or_within cell-matrix adhesion 11118207 Process
19261 GO:0032688 IMP involved_in negative regulation of interferon-beta production 17954568 Process
19261 GO:0032715 IMP involved_in negative regulation of interleukin-6 production 17954568 Process
19261 GO:0032720 IMP involved_in negative regulation of tumor necrosis factor production 17954568 Process
19261 GO:0045019 IMP involved_in negative regulation of nitric oxide biosynthetic process 17954568 Process
19261 GO:0046329 IMP involved_in negative regulation of JNK cascade 17954568 Process
19261 GO:0050765 IMP involved_in negative regulation of phagocytosis 21401967 Process
19261 GO:0050766 IDA acts_upstream_of_or_within positive regulation of phagocytosis 14634079 Process
19261 GO:0070373 IMP involved_in negative regulation of ERK1 and ERK2 cascade 17954568 Process
19261 GO:0071222 IDA involved_in cellular response to lipopolysaccharide 17954568 Process
19261 GO:0071641 IMP involved_in negative regulation of macrophage inflammatory protein 1 alpha production 17954568 Process
19261 GO:0071650 IMP involved_in negative regulation of chemokine (C-C motif) ligand 5 production 17954568 Process
19261 GO:0097530 IGI involved_in granulocyte migration 24026300 Process
19261 GO:1900016 IGI involved_in negative regulation of cytokine production involved in inflammatory response 23562609 Process
19261 GO:1900016 IMP involved_in negative regulation of cytokine production involved in inflammatory response 17954568 Process
19261 GO:1903720 IMP involved_in negative regulation of I-kappaB phosphorylation 17954568 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
19261 GO:0005515 IPI enables protein binding 11895767,12796776,14634079,14662855 Function
19261 GO:0019903 IPI enables protein phosphatase binding 17954568 Function
19261 GO:0045309 IPI enables protein phosphorylated amino acid binding 12393607 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
19261 GO:0005886 IDA located_in plasma membrane 14634079 Component