Gene Ontology

Gene Info

  • Species: Mouse (Mus musculus)
  • GeneID: 192656
  • Symbol: Ripk2
  • Description: receptor (TNFRSF)-interacting serine-threonine kinase 2

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
192656 GO:0001961 IMP acts_upstream_of_or_within positive regulation of cytokine-mediated signaling pathway 11894097 Process
192656 GO:0002250 IMP involved_in adaptive immune response 21469090 Process
192656 GO:0002827 IMP acts_upstream_of_or_within positive regulation of T-helper 1 type immune response 11894097 Process
192656 GO:0007249 IMP acts_upstream_of I-kappaB kinase/NF-kappaB signaling 11894097,11894098,18261938 Process
192656 GO:0007249 IMP involved_in I-kappaB kinase/NF-kappaB signaling 21469090 Process
192656 GO:0007254 IMP acts_upstream_of JNK cascade 11894097,11894098,18261938 Process
192656 GO:0010934 IMP acts_upstream_of macrophage cytokine production 11894098,18261938 Process
192656 GO:0019221 IMP acts_upstream_of cytokine-mediated signaling pathway 11894097 Process
192656 GO:0031663 IMP acts_upstream_of_or_within lipopolysaccharide-mediated signaling pathway 11894098 Process
192656 GO:0032602 IMP acts_upstream_of chemokine production 11894098 Process
192656 GO:0032609 IMP acts_upstream_of type II interferon production 11894097,11894098 Process
192656 GO:0032623 IMP acts_upstream_of interleukin-2 production 11894098 Process
192656 GO:0032635 IMP acts_upstream_of interleukin-6 production 11894098,18261938 Process
192656 GO:0032640 IMP acts_upstream_of tumor necrosis factor production 11894098,18261938 Process
192656 GO:0032722 IMP acts_upstream_of_or_within positive regulation of chemokine production 11894098 Process
192656 GO:0032729 IMP acts_upstream_of_or_within positive regulation of type II interferon production 11894097,11894098 Process
192656 GO:0032743 IMP acts_upstream_of_or_within positive regulation of interleukin-2 production 11894098 Process
192656 GO:0032755 IMP acts_upstream_of_or_within positive regulation of interleukin-6 production 11894098,18261938 Process
192656 GO:0032755 IMP involved_in positive regulation of interleukin-6 production 21887730 Process
192656 GO:0032760 IMP acts_upstream_of_or_within positive regulation of tumor necrosis factor production 11894098,18261938 Process
192656 GO:0032760 IMP involved_in positive regulation of tumor necrosis factor production 21887730 Process
192656 GO:0032874 IMP acts_upstream_of_or_within positive regulation of stress-activated MAPK cascade 11894097,11894098,18261938 Process
192656 GO:0033080 IMP acts_upstream_of immature T cell proliferation in thymus 11894098 Process
192656 GO:0033092 IMP acts_upstream_of_or_within positive regulation of immature T cell proliferation in thymus 11894098 Process
192656 GO:0034142 IMP acts_upstream_of_or_within toll-like receptor 4 signaling pathway 11894098 Process
192656 GO:0035739 IMP acts_upstream_of CD4-positive, alpha-beta T cell proliferation 11894097,11894098 Process
192656 GO:0042098 IMP acts_upstream_of_or_within T cell proliferation 14638696 Process
192656 GO:0043065 IDA acts_upstream_of_or_within positive regulation of apoptotic process 14663141 Process
192656 GO:0043123 IDA involved_in positive regulation of I-kappaB kinase/NF-kappaB signaling 17947236 Process
192656 GO:0043123 IMP acts_upstream_of_or_within positive regulation of I-kappaB kinase/NF-kappaB signaling 11894097,11894098,18261938 Process
192656 GO:0043281 IMP NOT acts_upstream_of_or_within regulation of cysteine-type endopeptidase activity involved in apoptotic process 15190255 Process
192656 GO:0043330 IMP acts_upstream_of_or_within response to exogenous dsRNA 11894098 Process
192656 GO:0045087 IMP involved_in innate immune response 21469090 Process
192656 GO:0045627 IMP acts_upstream_of_or_within positive regulation of T-helper 1 cell differentiation 11894097 Process
192656 GO:0046330 IMP acts_upstream_of_or_within positive regulation of JNK cascade 11894097,11894098,18261938 Process
192656 GO:0050830 IMP acts_upstream_of_or_within defense response to Gram-positive bacterium 11894097,11894098,18261938 Process
192656 GO:0050852 IMP acts_upstream_of_or_within T cell receptor signaling pathway 11894098 Process
192656 GO:0050852 IMP involved_in T cell receptor signaling pathway 21469090 Process
192656 GO:0051092 IMP acts_upstream_of_or_within positive regulation of NF-kappaB transcription factor activity 14638696 Process
192656 GO:0051092 IMP involved_in positive regulation of NF-kappaB transcription factor activity 21887730 Process
192656 GO:0051403 IMP acts_upstream_of stress-activated MAPK cascade 11894097,11894098,18261938 Process
192656 GO:0060907 IMP acts_upstream_of_or_within positive regulation of macrophage cytokine production 11894098,18261938 Process
192656 GO:0070371 IDA acts_upstream_of ERK1 and ERK2 cascade 18261938 Process
192656 GO:0070371 IMP acts_upstream_of ERK1 and ERK2 cascade 11894098 Process
192656 GO:0070374 IDA acts_upstream_of_or_within positive regulation of ERK1 and ERK2 cascade 18261938 Process
192656 GO:0070374 IMP acts_upstream_of_or_within positive regulation of ERK1 and ERK2 cascade 11894098 Process
192656 GO:0070427 IMP acts_upstream_of_or_within nucleotide-binding oligomerization domain containing 1 signaling pathway 11894098 Process
192656 GO:0070431 IDA involved_in nucleotide-binding oligomerization domain containing 2 signaling pathway 17947236 Process
192656 GO:0070431 IMP acts_upstream_of_or_within nucleotide-binding oligomerization domain containing 2 signaling pathway 11894098 Process
192656 GO:0070555 IMP acts_upstream_of_or_within response to interleukin-1 11894098 Process
192656 GO:0070671 IMP acts_upstream_of_or_within response to interleukin-12 11894097,11894098 Process
192656 GO:0070673 IMP acts_upstream_of_or_within response to interleukin-18 11894097,11894098 Process
192656 GO:0071222 IMP acts_upstream_of_or_within cellular response to lipopolysaccharide 11894097,11894098 Process
192656 GO:0071223 IMP acts_upstream_of_or_within cellular response to lipoteichoic acid 11894098 Process
192656 GO:0071224 IMP acts_upstream_of_or_within cellular response to peptidoglycan 11894098 Process
192656 GO:0071225 IDA involved_in cellular response to muramyl dipeptide 17947236 Process
192656 GO:0098792 IMP acts_upstream_of xenophagy 22033934 Process
192656 GO:1904417 IMP acts_upstream_of_or_within positive regulation of xenophagy 22033934 Process
192656 GO:2000563 IMP acts_upstream_of_or_within positive regulation of CD4-positive, alpha-beta T cell proliferation 11894097,11894098 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
192656 GO:0004674 IDA enables protein serine/threonine kinase activity 19473975 Function