Gene Ontology

Gene Info

  • Species:Mouse (Mus musculus)
  • GeneID:19877
  • Symbol:Rock1
  • Description:Rho-associated coiled-coil containing protein kinase 1

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
19877 GO:0001726 IDA located_in ruffle 16741948 Component
19877 GO:0005856 IDA located_in cytoskeleton 16741948 Component
19877 GO:0005886 IDA located_in plasma membrane 16741948 Component
19877 GO:0010494 IDA located_in cytoplasmic stress granule 27430620 Component
19877 GO:0030027 IDA located_in lamellipodium 16741948 Component
19877 GO:0098685 IDA is_active_in Schaffer collateral - CA1 synapse 30826947 Component
19877 GO:0098685 IMP is_active_in Schaffer collateral - CA1 synapse 30826947 Component

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
19877 GO:0001837 IGI involved_in epithelial to mesenchymal transition 15464581 Process
19877 GO:0003383 IGI acts_upstream_of_or_within apical constriction 21685893 Process
19877 GO:0030036 IGI acts_upstream_of_or_within actin cytoskeleton organization 16249236 Process
19877 GO:0030036 IGI involved_in actin cytoskeleton organization 15464581 Process
19877 GO:0032060 IMP acts_upstream_of_or_within bleb assembly 17135244 Process
19877 GO:0032956 IMP involved_in regulation of actin cytoskeleton organization 30115939 Process
19877 GO:0032970 IGI acts_upstream_of_or_within regulation of actin filament-based process 21685893 Process
19877 GO:0042326 IMP involved_in negative regulation of phosphorylation 30115939 Process
19877 GO:0051451 IMP involved_in myoblast migration 17654484 Process
19877 GO:0051894 IMP involved_in positive regulation of focal adhesion assembly 17654484 Process
19877 GO:0061157 IMP involved_in mRNA destabilization 29353861 Process
19877 GO:0071559 IGI involved_in response to transforming growth factor beta 28679962 Process
19877 GO:0090128 IDA involved_in regulation of synapse maturation 30826947 Process
19877 GO:0090128 IMP involved_in regulation of synapse maturation 30826947 Process
19877 GO:0090521 IMP involved_in podocyte cell migration 30115939 Process
19877 GO:0097049 IMP acts_upstream_of motor neuron apoptotic process 15071095 Process
19877 GO:0097746 IMP involved_in blood vessel diameter maintenance 29353861 Process
19877 GO:1990776 IGI involved_in response to angiotensin 28679962 Process
19877 GO:2000672 IMP acts_upstream_of_or_within negative regulation of motor neuron apoptotic process 15071095 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
19877 GO:0005515 IPI enables protein binding 16741948,17654484,18946488 Function