Gene Ontology

Gene Info

  • Species:Mouse (Mus musculus)
  • GeneID:19878
  • Symbol:Rock2
  • Description:Rho-associated coiled-coil containing protein kinase 2

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
19878 GO:0001837 IGI involved_in epithelial to mesenchymal transition 15464581 Process
19878 GO:0001843 IGI acts_upstream_of_or_within neural tube closure 17229766 Process
19878 GO:0002931 IMP involved_in response to ischemia 29353861 Process
19878 GO:0006468 IMP acts_upstream_of_or_within protein phosphorylation 18524939 Process
19878 GO:0008625 IGI acts_upstream_of_or_within extrinsic apoptotic signaling pathway via death domain receptors 16365167 Process
19878 GO:0010613 IMP involved_in positive regulation of cardiac muscle hypertrophy 28679962 Process
19878 GO:0010628 IMP involved_in positive regulation of gene expression 28679962 Process
19878 GO:0010629 IMP involved_in negative regulation of gene expression 29353861 Process
19878 GO:0010825 IMP acts_upstream_of_or_within positive regulation of centrosome duplication 17015463 Process
19878 GO:0018105 IMP involved_in peptidyl-serine phosphorylation 24305806 Process
19878 GO:0018107 IMP involved_in peptidyl-threonine phosphorylation 29353861 Process
19878 GO:0030036 IGI acts_upstream_of_or_within actin cytoskeleton organization 16249236 Process
19878 GO:0030036 IGI involved_in actin cytoskeleton organization 15464581 Process
19878 GO:0031644 IMP involved_in regulation of nervous system process 29353861 Process
19878 GO:0042752 IMP involved_in regulation of circadian rhythm 23172836 Process
19878 GO:0043410 IMP involved_in positive regulation of MAPK cascade 28679962 Process
19878 GO:0045019 IMP involved_in negative regulation of nitric oxide biosynthetic process 29353861 Process
19878 GO:0048813 IGI acts_upstream_of_or_within dendrite morphogenesis 23365224 Process
19878 GO:0051246 IMP involved_in regulation of protein metabolic process 24305806 Process
19878 GO:0051298 IMP acts_upstream_of centrosome duplication 17015463 Process
19878 GO:0061157 IMP involved_in mRNA destabilization 29353861 Process
19878 GO:0071559 IGI involved_in response to transforming growth factor beta 28679962 Process
19878 GO:0090128 IDA involved_in regulation of synapse maturation 30826947 Process
19878 GO:0090128 IMP involved_in regulation of synapse maturation 30826947 Process
19878 GO:0097746 IMP involved_in blood vessel diameter maintenance 29353861 Process
19878 GO:0098974 IDA involved_in postsynaptic actin cytoskeleton organization 18718479 Process
19878 GO:0098974 IMP involved_in postsynaptic actin cytoskeleton organization 18718479 Process
19878 GO:0110061 IMP involved_in regulation of angiotensin-activated signaling pathway 28679962 Process
19878 GO:1900037 IMP involved_in regulation of cellular response to hypoxia 29353861 Process
19878 GO:1902004 IMP involved_in positive regulation of amyloid-beta formation 24305806 Process
19878 GO:1902961 IMP involved_in positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process 24305806 Process
19878 GO:1902993 IMP involved_in positive regulation of amyloid precursor protein catabolic process 24305806 Process
19878 GO:1905145 IMP involved_in cellular response to acetylcholine 29353861 Process
19878 GO:1905205 IMP involved_in positive regulation of connective tissue replacement 28679962 Process
19878 GO:1990776 IGI involved_in response to angiotensin 28679962 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
19878 GO:0004672 IDA enables protein kinase activity 25959411 Function
19878 GO:0004674 IMP enables protein serine/threonine kinase activity 24305806,29353861 Function
19878 GO:0005515 IPI enables protein binding 16365167,17015463,28089576 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
19878 GO:0005813 IDA located_in centrosome 17015463 Component
19878 GO:0031616 IDA located_in spindle pole centrosome 17015463 Component
19878 GO:0098685 IDA is_active_in Schaffer collateral - CA1 synapse 18718479,30826947 Component
19878 GO:0098685 IMP is_active_in Schaffer collateral - CA1 synapse 18718479,30826947 Component
19878 GO:0098978 IDA is_active_in glutamatergic synapse 18718479 Component
19878 GO:0098978 IMP is_active_in glutamatergic synapse 18718479 Component