Gene Ontology

Gene Info

  • Species:Mouse (Mus musculus)
  • GeneID:20319
  • Symbol:Sfrp2
  • Description:secreted frizzled-related protein 2

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
20319 GO:0001569 IDA involved_in branching involved in blood vessel morphogenesis 19458075 Process
20319 GO:0001756 IGI acts_upstream_of_or_within somitogenesis 16467359 Process
20319 GO:0001843 IGI acts_upstream_of_or_within neural tube closure 19850029 Process
20319 GO:0002063 IMP acts_upstream_of_or_within chondrocyte development 18729207 Process
20319 GO:0003402 IGI acts_upstream_of planar cell polarity pathway involved in axis elongation 18257070 Process
20319 GO:0006915 IMP acts_upstream_of_or_within apoptotic process 18729207 Process
20319 GO:0007501 IGI acts_upstream_of mesodermal cell fate specification 17462603 Process
20319 GO:0008284 IDA involved_in positive regulation of cell population proliferation 10980594 Process
20319 GO:0008584 IGI acts_upstream_of_or_within male gonad development 19100252 Process
20319 GO:0009410 IDA involved_in response to xenobiotic stimulus 19778523 Process
20319 GO:0009952 IGI acts_upstream_of_or_within anterior/posterior pattern specification 16467359 Process
20319 GO:0010629 IDA involved_in negative regulation of gene expression 10980594 Process
20319 GO:0010659 IDA acts_upstream_of cardiac muscle cell apoptotic process 17251350 Process
20319 GO:0010667 IDA acts_upstream_of_or_within negative regulation of cardiac muscle cell apoptotic process 17251350 Process
20319 GO:0010950 IDA acts_upstream_of_or_within positive regulation of endopeptidase activity 19079247 Process
20319 GO:0010975 IDA involved_in regulation of neuron projection development 22290867 Process
20319 GO:0021915 IGI acts_upstream_of_or_within neural tube development 19850029 Process
20319 GO:0030111 IDA involved_in regulation of Wnt signaling pathway 9391078 Process
20319 GO:0030178 IDA involved_in negative regulation of Wnt signaling pathway 10654605,11357136 Process
20319 GO:0030199 IMP acts_upstream_of_or_within collagen fibril organization 19079247 Process
20319 GO:0030307 IDA involved_in positive regulation of cell growth 10980594 Process
20319 GO:0030336 IDA involved_in negative regulation of cell migration 10980594 Process
20319 GO:0030509 IGI acts_upstream_of BMP signaling pathway 19850029 Process
20319 GO:0030514 IDA acts_upstream_of_or_within negative regulation of BMP signaling pathway 19850029 Process
20319 GO:0030514 IGI acts_upstream_of_or_within negative regulation of BMP signaling pathway 19850029 Process
20319 GO:0031668 IDA acts_upstream_of_or_within cellular response to extracellular stimulus 10322635 Process
20319 GO:0033138 IDA involved_in positive regulation of peptidyl-serine phosphorylation 20723538 Process
20319 GO:0036342 IMP acts_upstream_of_or_within post-anal tail morphogenesis 18729207 Process
20319 GO:0042127 IMP acts_upstream_of_or_within regulation of cell population proliferation 18729207 Process
20319 GO:0042662 IGI acts_upstream_of_or_within negative regulation of mesodermal cell fate specification 17462603 Process
20319 GO:0042733 IMP acts_upstream_of_or_within embryonic digit morphogenesis 18729207 Process
20319 GO:0042981 IMP acts_upstream_of_or_within regulation of apoptotic process 18729207 Process
20319 GO:0043154 IDA acts_upstream_of_or_within negative regulation of cysteine-type endopeptidase activity involved in apoptotic process 17251350 Process
20319 GO:0043508 IGI acts_upstream_of_or_within negative regulation of JUN kinase activity 19300477 Process
20319 GO:0045669 IGI acts_upstream_of_or_within positive regulation of osteoblast differentiation 18166153 Process
20319 GO:0045766 IDA involved_in positive regulation of angiogenesis 19458075 Process
20319 GO:0045944 IDA involved_in positive regulation of transcription by RNA polymerase II 20723538 Process
20319 GO:0046546 IGI acts_upstream_of_or_within development of primary male sexual characteristics 19100252 Process
20319 GO:0048546 IGI acts_upstream_of_or_within digestive tract morphogenesis 19300477 Process
20319 GO:0048866 IGI acts_upstream_of stem cell fate specification 17462603 Process
20319 GO:0050732 IDA involved_in negative regulation of peptidyl-tyrosine phosphorylation 10980594 Process
20319 GO:0051216 IMP acts_upstream_of_or_within cartilage development 18729207 Process
20319 GO:0060028 IGI acts_upstream_of_or_within convergent extension involved in axis elongation 18257070 Process
20319 GO:0060070 IGI acts_upstream_of canonical Wnt signaling pathway 18257070,19850029,19896444 Process
20319 GO:0061056 IEP involved_in sclerotome development 10654605 Process
20319 GO:0061185 IDA involved_in negative regulation of dermatome development 10654605 Process
20319 GO:0071425 IDA involved_in hematopoietic stem cell proliferation 19778523 Process
20319 GO:0071481 IDA involved_in cellular response to X-ray 19778523 Process
20319 GO:0090090 IDA acts_upstream_of_or_within negative regulation of canonical Wnt signaling pathway 17804636 Process
20319 GO:0090090 IGI acts_upstream_of_or_within negative regulation of canonical Wnt signaling pathway 17462603,18257070,19850029,19896444 Process
20319 GO:0090175 IGI acts_upstream_of_or_within regulation of establishment of planar polarity 19300477 Process
20319 GO:0090179 IGI acts_upstream_of_or_within planar cell polarity pathway involved in neural tube closure 18257070 Process
20319 GO:0090244 IGI acts_upstream_of_or_within Wnt signaling pathway involved in somitogenesis 18257070 Process
20319 GO:0090263 IDA involved_in positive regulation of canonical Wnt signaling pathway 19001373,20723538 Process
20319 GO:0090263 IGI acts_upstream_of_or_within positive regulation of canonical Wnt signaling pathway 18166153 Process
20319 GO:1902042 IDA involved_in negative regulation of extrinsic apoptotic signaling pathway via death domain receptors 9391078 Process
20319 GO:1904956 IGI involved_in regulation of midbrain dopaminergic neuron differentiation 22290867 Process
20319 GO:2000035 IDA involved_in regulation of stem cell division 19778523 Process
20319 GO:2000041 IGI acts_upstream_of_or_within negative regulation of planar cell polarity pathway involved in axis elongation 18257070 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
20319 GO:0005515 IPI enables protein binding 9096311,9853965,19079247,21078975 Function
20319 GO:0008047 IDA enables enzyme activator activity 19079247 Function
20319 GO:0017147 IPI enables Wnt-protein binding 17462603 Function
20319 GO:0048018 IDA enables receptor ligand activity 20723538 Function
20319 GO:0061133 IDA enables endopeptidase activator activity 19079247 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
20319 GO:0005615 IDA located_in extracellular space 9391078,10654605,10980594 Component