Gene Ontology

Gene Info

  • Species:Mouse (Mus musculus)
  • GeneID:20471
  • Symbol:Six1
  • Description:sine oculis-related homeobox 1

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
20471 GO:0000122 IDA acts_upstream_of_or_within negative regulation of transcription by RNA polymerase II 21281623 Process
20471 GO:0001657 IGI acts_upstream_of_or_within ureteric bud development 16018995 Process
20471 GO:0001657 IMP acts_upstream_of_or_within ureteric bud development 12783782 Process
20471 GO:0001658 IGI acts_upstream_of_or_within branching involved in ureteric bud morphogenesis 12783782 Process
20471 GO:0001759 IMP acts_upstream_of_or_within organ induction 12783782 Process
20471 GO:0001822 IMP involved_in kidney development 16934795 Process
20471 GO:0003151 IGI acts_upstream_of_or_within outflow tract morphogenesis 21364285 Process
20471 GO:0006355 IDA acts_upstream_of_or_within regulation of DNA-templated transcription 14628042 Process
20471 GO:0007219 IMP involved_in Notch signaling pathway 28455376 Process
20471 GO:0007382 IMP involved_in specification of segmental identity, maxillary segment 28455376 Process
20471 GO:0007389 IGI acts_upstream_of_or_within pattern specification process 16530750 Process
20471 GO:0007389 IMP acts_upstream_of_or_within pattern specification process 16916509 Process
20471 GO:0007519 IGI acts_upstream_of_or_within skeletal muscle tissue development 15788460 Process
20471 GO:0007519 IMP involved_in skeletal muscle tissue development 17592144 Process
20471 GO:0007605 IMP acts_upstream_of_or_within sensory perception of sound 12874121 Process
20471 GO:0008582 IGI acts_upstream_of_or_within regulation of synaptic assembly at neuromuscular junction 21884692 Process
20471 GO:0010467 IMP involved_in gene expression 28455376 Process
20471 GO:0010468 IGI acts_upstream_of_or_within regulation of gene expression 21884692 Process
20471 GO:0014033 IGI involved_in neural crest cell differentiation 28455376 Process
20471 GO:0014842 IDA involved_in regulation of skeletal muscle satellite cell proliferation 20696153 Process
20471 GO:0021610 IMP acts_upstream_of_or_within facial nerve morphogenesis 12874121 Process
20471 GO:0022008 IMP involved_in neurogenesis 19027001 Process
20471 GO:0030855 IMP acts_upstream_of_or_within epithelial cell differentiation 16530750 Process
20471 GO:0030878 IMP acts_upstream_of_or_within thyroid gland development 16530750 Process
20471 GO:0030910 IMP involved_in olfactory placode formation 19027001 Process
20471 GO:0032880 IGI acts_upstream_of_or_within regulation of protein localization 21884692 Process
20471 GO:0035909 IGI acts_upstream_of_or_within aorta morphogenesis 21364285 Process
20471 GO:0042472 IGI acts_upstream_of_or_within inner ear morphogenesis 15788460 Process
20471 GO:0042474 IMP acts_upstream_of_or_within middle ear morphogenesis 12874121 Process
20471 GO:0043066 IMP involved_in negative regulation of apoptotic process 15788460,19027001 Process
20471 GO:0043524 IMP involved_in negative regulation of neuron apoptotic process 16938278 Process
20471 GO:0043586 IMP involved_in tongue development 21978088 Process
20471 GO:0045664 IGI acts_upstream_of_or_within regulation of neuron differentiation 22513373 Process
20471 GO:0045664 IMP acts_upstream_of_or_within regulation of neuron differentiation 15496442 Process
20471 GO:0045893 IDA involved_in positive regulation of DNA-templated transcription 19962975,20696153 Process
20471 GO:0045893 IMP involved_in positive regulation of DNA-templated transcription 17300925,17592144 Process
20471 GO:0045944 IDA acts_upstream_of_or_within positive regulation of transcription by RNA polymerase II 15955062 Process
20471 GO:0045944 IGI acts_upstream_of_or_within positive regulation of transcription by RNA polymerase II 21364285,22513373 Process
20471 GO:0048538 IGI acts_upstream_of_or_within thymus development 16530750 Process
20471 GO:0048538 IMP acts_upstream_of_or_within thymus development 16530750 Process
20471 GO:0048665 IGI acts_upstream_of_or_within neuron fate specification 22513373 Process
20471 GO:0048699 IMP involved_in generation of neurons 16938278 Process
20471 GO:0048701 IGI acts_upstream_of_or_within embryonic cranial skeleton morphogenesis 20515681 Process
20471 GO:0048704 IGI acts_upstream_of_or_within embryonic skeletal system morphogenesis 15788460 Process
20471 GO:0048705 IMP acts_upstream_of_or_within skeletal system morphogenesis 12874121 Process
20471 GO:0048839 IMP involved_in inner ear development 19389353 Process
20471 GO:0048856 IGI acts_upstream_of_or_within anatomical structure development 16530750 Process
20471 GO:0050678 IMP involved_in regulation of epithelial cell proliferation 19027001 Process
20471 GO:0051450 IGI acts_upstream_of myoblast proliferation 20110314 Process
20471 GO:0051451 IGI acts_upstream_of_or_within myoblast migration 15788460 Process
20471 GO:0060037 IGI acts_upstream_of_or_within pharyngeal system development 21364285 Process
20471 GO:0060037 IMP involved_in pharyngeal system development 16530750 Process
20471 GO:0061055 IMP involved_in myotome development 15788460,19962975 Process
20471 GO:0061197 IMP involved_in fungiform papilla morphogenesis 21978088 Process
20471 GO:0061551 IMP involved_in trigeminal ganglion development 16938278 Process
20471 GO:0071599 IGI acts_upstream_of_or_within otic vesicle development 22513373 Process
20471 GO:0071599 IMP acts_upstream_of_or_within otic vesicle development 16916509 Process
20471 GO:0072075 IMP involved_in metanephric mesenchyme development 17300925 Process
20471 GO:0072095 IMP involved_in regulation of branch elongation involved in ureteric bud branching 17300925 Process
20471 GO:0072107 IMP involved_in positive regulation of ureteric bud formation 17300925 Process
20471 GO:0072172 IMP involved_in mesonephric tubule formation 17300925 Process
20471 GO:0072193 IMP acts_upstream_of_or_within ureter smooth muscle cell differentiation 20110314 Process
20471 GO:0072198 IGI acts_upstream_of mesenchymal cell proliferation involved in ureter development 20110314 Process
20471 GO:0072513 IGI acts_upstream_of_or_within positive regulation of secondary heart field cardioblast proliferation 21364285 Process
20471 GO:0086100 IMP involved_in endothelin receptor signaling pathway 28455376 Process
20471 GO:0090103 IMP acts_upstream_of_or_within cochlea morphogenesis 12874121 Process
20471 GO:0090190 IGI acts_upstream_of_or_within positive regulation of branching involved in ureteric bud morphogenesis 21281623 Process
20471 GO:0090190 IMP involved_in positive regulation of branching involved in ureteric bud morphogenesis 17300925 Process
20471 GO:0090336 IMP involved_in positive regulation of brown fat cell differentiation 27923061 Process
20471 GO:2000288 IGI acts_upstream_of_or_within positive regulation of myoblast proliferation 20110314 Process
20471 GO:2000729 IGI acts_upstream_of_or_within positive regulation of mesenchymal cell proliferation involved in ureter development 20110314 Process
20471 GO:2001014 IDA involved_in regulation of skeletal muscle cell differentiation 20696153 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
20471 GO:0003682 IGI enables chromatin binding 19008232 Function
20471 GO:0003700 IDA enables DNA-binding transcription factor activity 15955062 Function
20471 GO:0005515 IPI enables protein binding 11734542,12215533,15141091,19008232,20110314,22513373..... Function
20471 GO:0043565 IDA enables sequence-specific DNA binding 9826681,17098221 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
20471 GO:0005634 IDA located_in nucleus 9826681,14628042 Component
20471 GO:0005667 IDA part_of transcription regulator complex 14628042 Component
20471 GO:0005667 IPI part_of transcription regulator complex 19008232 Component