Gene Ontology

Gene Info

  • Species:Mouse (Mus musculus)
  • GeneID:20472
  • Symbol:Six2
  • Description:sine oculis-related homeobox 2

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
20472 GO:0000978 IDA enables RNA polymerase II cis-regulatory region sequence-specific DNA binding 15327782 Function
20472 GO:0001228 IDA enables DNA-binding transcription activator activity, RNA polymerase II-specific 15327782 Function
20472 GO:0003700 IDA enables DNA-binding transcription factor activity 15327782 Function
20472 GO:0005515 IPI enables protein binding 11734542,12215533,20956555 Function
20472 GO:0008134 IPI enables transcription factor binding 22902740,24598167 Function
20472 GO:0043565 IDA enables sequence-specific DNA binding 8814301,15327782 Function
20472 GO:0044877 IDA enables protein-containing complex binding 17785448 Function

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
20472 GO:0001656 IMP acts_upstream_of_or_within metanephros development 17036046 Process
20472 GO:0001822 IMP involved_in kidney development 17036046 Process
20472 GO:0002062 IMP acts_upstream_of_or_within chondrocyte differentiation 20515681 Process
20472 GO:0003337 IEP involved_in mesenchymal to epithelial transition involved in metanephros morphogenesis 10322633 Process
20472 GO:0006606 IDA acts_upstream_of_or_within protein import into nucleus 16024294 Process
20472 GO:0007501 IDA involved_in mesodermal cell fate specification 17785448 Process
20472 GO:0008283 IMP acts_upstream_of_or_within cell population proliferation 20515681 Process
20472 GO:0009948 IDA involved_in anterior/posterior axis specification 18321982 Process
20472 GO:0030278 IMP involved_in regulation of ossification 20515681 Process
20472 GO:0030855 IMP acts_upstream_of epithelial cell differentiation 17036046 Process
20472 GO:0030857 IMP acts_upstream_of_or_within negative regulation of epithelial cell differentiation 17036046 Process
20472 GO:0032330 IMP involved_in regulation of chondrocyte differentiation 20515681 Process
20472 GO:0042474 IGI acts_upstream_of_or_within middle ear morphogenesis 15634706 Process
20472 GO:0045944 IDA acts_upstream_of_or_within positive regulation of transcription by RNA polymerase II 15327782 Process
20472 GO:0048557 IMP involved_in embryonic digestive tract morphogenesis 19660448 Process
20472 GO:0048701 IMP acts_upstream_of_or_within embryonic cranial skeleton morphogenesis 20515681 Process
20472 GO:0048704 IGI acts_upstream_of_or_within embryonic skeletal system morphogenesis 15634706 Process
20472 GO:0072006 IMP involved_in nephron development 18682239 Process
20472 GO:0072028 IMP involved_in nephron morphogenesis 17036046 Process
20472 GO:0072038 IDA involved_in mesenchymal stem cell maintenance involved in nephron morphogenesis 22902740,24598167 Process
20472 GO:0072038 IMP involved_in mesenchymal stem cell maintenance involved in nephron morphogenesis 18682239,21350016 Process
20472 GO:0072137 IGI acts_upstream_of_or_within condensed mesenchymal cell proliferation 26116661 Process
20472 GO:0072161 IMP involved_in mesenchymal cell differentiation involved in kidney development 17036046 Process
20472 GO:0090189 IMP involved_in regulation of branching involved in ureteric bud morphogenesis 17036046 Process
20472 GO:0097168 IMP involved_in mesenchymal stem cell proliferation 21350016 Process
20472 GO:1902732 IMP involved_in positive regulation of chondrocyte proliferation 20515681 Process

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
20472 GO:0005634 IDA located_in nucleus 8814301,15327782 Component