Gene Ontology

Gene Info

  • Species:Human (Homo sapiens)
  • GeneID:2074
  • Symbol:ERCC6
  • Description:ERCC excision repair 6, chromatin remodeling factor

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
2074 GO:0000012 IDA involved_in single strand break repair 29545921 Process
2074 GO:0000077 IMP involved_in DNA damage checkpoint signaling 25820262 Process
2074 GO:0006283 IMP involved_in transcription-coupled nucleotide-excision repair 10564257,26620705 Process
2074 GO:0006284 IMP involved_in base-excision repair 9973627 Process
2074 GO:0006979 IDA involved_in response to oxidative stress 16107709 Process
2074 GO:0006979 IGI acts_upstream_of_or_within response to oxidative stress 17626041 Process
2074 GO:0022008 IMP involved_in neurogenesis 24874740 Process
2074 GO:0030182 IMP involved_in neuron differentiation 24874740 Process
2074 GO:0031175 IMP involved_in neuron projection development 24874740 Process
2074 GO:0032784 IDA involved_in regulation of DNA-templated transcription elongation 9326587 Process
2074 GO:0032786 IDA involved_in positive regulation of DNA-templated transcription, elongation 9326587 Process
2074 GO:0045739 IGI involved_in positive regulation of DNA repair 22483866 Process
2074 GO:0045739 IMP involved_in positive regulation of DNA repair 22483866 Process
2074 GO:0045945 IDA involved_in positive regulation of transcription by RNA polymerase III 16603771 Process
2074 GO:0097680 IDA involved_in double-strand break repair via classical nonhomologous end joining 29545921 Process
2074 GO:1905168 IMP involved_in positive regulation of double-strand break repair via homologous recombination 25820262 Process
2074 GO:2001033 IMP involved_in negative regulation of double-strand break repair via nonhomologous end joining 25820262 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
2074 GO:0003677 IDA enables DNA binding 8999876,12560492,16107709 Function
2074 GO:0003678 IDA NOT enables DNA helicase activity 8999876 Function
2074 GO:0003682 IDA enables chromatin binding 26620705 Function
2074 GO:0003682 IMP enables chromatin binding 25820262 Function
2074 GO:0005515 IPI enables protein binding 7663514,7664335,8999876,10944529,16107709,16246722,17626041,22..... Function
2074 GO:0005524 IDA enables ATP binding 12560492,16107709 Function
2074 GO:0008094 IDA enables ATP-dependent activity, acting on DNA 8999876,12560492,16107709 Function
2074 GO:0008094 IMP enables ATP-dependent activity, acting on DNA 25820262 Function
2074 GO:0030296 IDA enables protein tyrosine kinase activator activity 17626041 Function
2074 GO:0140658 IMP enables ATP-dependent chromatin remodeler activity 29203878 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
2074 GO:0005634 IDA located_in nucleus 12560492,17626041 Component
2074 GO:0005654 IDA located_in nucleoplasm 16107709 Component
2074 GO:0005730 IDA located_in nucleolus 16107709,17626041 Component
2074 GO:0008023 IDA part_of transcription elongation factor complex 9326587 Component
2074 GO:0090734 IDA located_in site of DNA damage 28292928 Component
2074 GO:0110016 IDA part_of B-WICH complex 16603771 Component