Gene Ontology

Gene Info

  • Species:Mouse (Mus musculus)
  • GeneID:211323
  • Symbol:Nrg1
  • Description:neuregulin 1

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
211323 GO:0000165 IDA acts_upstream_of_or_within MAPK cascade 8707830 Process
211323 GO:0000902 IDA acts_upstream_of_or_within cell morphogenesis 9247262 Process
211323 GO:0001764 IGI acts_upstream_of_or_within neuron migration 9247262 Process
211323 GO:0003161 IDA acts_upstream_of_or_within cardiac conduction system development 12149465 Process
211323 GO:0007399 IMP acts_upstream_of_or_within nervous system development 8643489 Process
211323 GO:0007416 IMP acts_upstream_of_or_within synapse assembly 10707974 Process
211323 GO:0007422 IMP acts_upstream_of_or_within peripheral nervous system development 7477375,9362461 Process
211323 GO:0007507 IMP acts_upstream_of_or_within heart development 7477375,8643489,9362461 Process
211323 GO:0007517 IMP acts_upstream_of_or_within muscle organ development 12495620 Process
211323 GO:0007626 IMP acts_upstream_of_or_within locomotory behavior 10762692 Process
211323 GO:0010001 IMP acts_upstream_of_or_within glial cell differentiation 12649319 Process
211323 GO:0010628 IDA acts_upstream_of_or_within positive regulation of gene expression 24364879 Process
211323 GO:0014037 IMP acts_upstream_of_or_within Schwann cell differentiation 16606832 Process
211323 GO:0021781 IDA acts_upstream_of_or_within glial cell fate commitment 21068328 Process
211323 GO:0021842 IMP acts_upstream_of_or_within chemorepulsion involved in interneuron migration from the subpallium to the cortex 22376909 Process
211323 GO:0022011 IMP acts_upstream_of_or_within myelination in peripheral nervous system 25453108 Process
211323 GO:0030163 IDA acts_upstream_of protein catabolic process 20448149 Process
211323 GO:0038130 IDA involved_in ERBB4 signaling pathway 16446434 Process
211323 GO:0042177 IDA acts_upstream_of_or_within negative regulation of protein catabolic process 20448149 Process
211323 GO:0043491 IDA acts_upstream_of protein kinase B signaling 20448149 Process
211323 GO:0045213 IMP acts_upstream_of_or_within neurotransmitter receptor metabolic process 9110980 Process
211323 GO:0045595 IMP acts_upstream_of_or_within regulation of cell differentiation 9892702,11425901 Process
211323 GO:0045860 IDA acts_upstream_of_or_within positive regulation of protein kinase activity 7816098,10597237 Process
211323 GO:0046579 IDA acts_upstream_of_or_within positive regulation of Ras protein signal transduction 8707830 Process
211323 GO:0048663 IMP acts_upstream_of_or_within neuron fate commitment 11425901 Process
211323 GO:0048709 IMP acts_upstream_of_or_within oligodendrocyte differentiation 11756753 Process
211323 GO:0048738 IDA acts_upstream_of_or_within cardiac muscle tissue development 24364879 Process
211323 GO:0050731 IDA acts_upstream_of_or_within positive regulation of peptidyl-tyrosine phosphorylation 8702723,21186272 Process
211323 GO:0051155 IMP involved_in positive regulation of striated muscle cell differentiation 17336907 Process
211323 GO:0051897 IDA acts_upstream_of_or_within positive regulation of protein kinase B signaling 20448149 Process
211323 GO:0055007 IMP involved_in cardiac muscle cell differentiation 17336907 Process
211323 GO:0070886 IGI acts_upstream_of_or_within positive regulation of calcineurin-NFAT signaling cascade 19179536 Process
211323 GO:0099527 IDA involved_in postsynapse to nucleus signaling pathway 15494726 Process
211323 GO:0099527 IMP involved_in postsynapse to nucleus signaling pathway 15494726 Process
211323 GO:0099560 EXP involved_in synaptic membrane adhesion 10686589 Process
211323 GO:0099560 IDA involved_in synaptic membrane adhesion 10686589 Process
211323 GO:0099560 IMP involved_in synaptic membrane adhesion 10686589 Process
211323 GO:0099560 IPI involved_in synaptic membrane adhesion 10686589 Process
211323 GO:1905606 IDA involved_in regulation of presynapse assembly 20393464 Process
211323 GO:1905606 IMP involved_in regulation of presynapse assembly 20393464 Process
211323 GO:2000727 IMP involved_in positive regulation of cardiac muscle cell differentiation 17336907 Process
211323 GO:2001223 IDA acts_upstream_of_or_within negative regulation of neuron migration 22376909 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
211323 GO:0005176 IDA enables ErbB-2 class receptor binding 11425901 Function
211323 GO:0005176 IGI enables ErbB-2 class receptor binding 9247262 Function
211323 GO:0005515 IPI enables protein binding 19935654 Function
211323 GO:0045499 IDA enables chemorepellent activity 22376909 Function
211323 GO:0048018 IDA enables receptor ligand activity 16446434 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
211323 GO:0005737 IDA located_in cytoplasm 9789034 Component
211323 GO:0005886 IDA located_in plasma membrane 9789034,11425901 Component
211323 GO:0030424 IDA located_in axon 20220021 Component
211323 GO:0031594 IDA located_in neuromuscular junction 7589796 Component
211323 GO:0045202 IDA located_in synapse 7816098 Component
211323 GO:0048787 IDA is_active_in presynaptic active zone membrane 10686589 Component
211323 GO:0097471 EXP is_active_in mossy fiber rosette 10686589 Component
211323 GO:0097471 IDA is_active_in mossy fiber rosette 10686589 Component
211323 GO:0097471 IMP is_active_in mossy fiber rosette 10686589 Component
211323 GO:0097471 IPI is_active_in mossy fiber rosette 10686589 Component
211323 GO:0098794 IDA is_active_in postsynapse 24803543 Component
211323 GO:0098839 IDA is_active_in postsynaptic density membrane 10686589 Component
211323 GO:0098978 IDA is_active_in glutamatergic synapse 15494726 Component
211323 GO:0098978 IMP is_active_in glutamatergic synapse 15494726 Component
211323 GO:0098982 IDA is_active_in GABA-ergic synapse 20393464 Component
211323 GO:0098982 IMP is_active_in GABA-ergic synapse 20393464 Component