Gene Ontology

Gene Info

  • Species:Mouse (Mus musculus)
  • GeneID:21380
  • Symbol:Tbx1
  • Description:T-box 1

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
21380 GO:0000122 IMP involved_in negative regulation of transcription by RNA polymerase II 20122914 Process
21380 GO:0001525 IMP acts_upstream_of_or_within angiogenesis 11971873 Process
21380 GO:0001568 IGI acts_upstream_of_or_within blood vessel development 16399080 Process
21380 GO:0001568 IMP acts_upstream_of_or_within blood vessel development 11242049,16284121 Process
21380 GO:0001755 IMP acts_upstream_of_or_within neural crest cell migration 15652707,20501333 Process
21380 GO:0001934 IMP involved_in positive regulation of protein phosphorylation 20807544 Process
21380 GO:0001945 IMP acts_upstream_of_or_within lymph vessel development 20439995 Process
21380 GO:0001974 IGI acts_upstream_of_or_within blood vessel remodeling 17000704 Process
21380 GO:0002053 IMP involved_in positive regulation of mesenchymal cell proliferation 18231833 Process
21380 GO:0003007 IMP acts_upstream_of_or_within heart morphogenesis 15175244,15190012,16696966,16914493 Process
21380 GO:0003148 IMP involved_in outflow tract septum morphogenesis 20807544 Process
21380 GO:0003151 IGI acts_upstream_of_or_within outflow tract morphogenesis 21364285 Process
21380 GO:0003151 IMP acts_upstream_of_or_within outflow tract morphogenesis 17916582,18583714 Process
21380 GO:0006357 IGI acts_upstream_of_or_within regulation of transcription by RNA polymerase II 20816801 Process
21380 GO:0007368 IMP acts_upstream_of_or_within determination of left/right symmetry 16556915 Process
21380 GO:0007389 IGI acts_upstream_of_or_within pattern specification process 16399080 Process
21380 GO:0007389 IMP acts_upstream_of_or_within pattern specification process 15385444,15652707 Process
21380 GO:0007498 IMP acts_upstream_of_or_within mesoderm development 11242110 Process
21380 GO:0007507 IGI acts_upstream_of_or_within heart development 16399080,16556915 Process
21380 GO:0007507 IMP acts_upstream_of_or_within heart development 11239417,11242110,11971873,16556915 Process
21380 GO:0007507 IMP involved_in heart development 21177346 Process
21380 GO:0007517 IMP acts_upstream_of_or_within muscle organ development 15385444 Process
21380 GO:0007605 IMP acts_upstream_of_or_within sensory perception of sound 15190012,16600992 Process
21380 GO:0008283 IMP acts_upstream_of cell population proliferation 16141220 Process
21380 GO:0008284 IMP acts_upstream_of_or_within positive regulation of cell population proliferation 16141220 Process
21380 GO:0009952 IGI acts_upstream_of_or_within anterior/posterior pattern specification 16399080 Process
21380 GO:0009952 IMP acts_upstream_of_or_within anterior/posterior pattern specification 15084464 Process
21380 GO:0010463 IDA acts_upstream_of_or_within mesenchymal cell proliferation 16914493 Process
21380 GO:0021644 IMP acts_upstream_of_or_within vagus nerve morphogenesis 20939858 Process
21380 GO:0030878 IGI acts_upstream_of_or_within thyroid gland development 19389367 Process
21380 GO:0030878 IMP acts_upstream_of_or_within thyroid gland development 15190012,17164259,19389367 Process
21380 GO:0035176 IMP acts_upstream_of_or_within social behavior 16684884 Process
21380 GO:0035909 IGI acts_upstream_of_or_within aorta morphogenesis 21364285 Process
21380 GO:0035909 IMP acts_upstream_of_or_within aorta morphogenesis 17916582 Process
21380 GO:0036305 IMP acts_upstream_of_or_within ameloblast differentiation 19233155,20816801 Process
21380 GO:0042471 IMP acts_upstream_of_or_within ear morphogenesis 15190012 Process
21380 GO:0042472 IMP acts_upstream_of_or_within inner ear morphogenesis 12913075,15084464,15652707,16600992 Process
21380 GO:0042473 IMP acts_upstream_of_or_within outer ear morphogenesis 16600992 Process
21380 GO:0042474 IMP acts_upstream_of_or_within middle ear morphogenesis 15652707,16600992,20501333 Process
21380 GO:0042475 IMP acts_upstream_of_or_within odontogenesis of dentin-containing tooth 19233155,20816801 Process
21380 GO:0042693 IMP acts_upstream_of_or_within muscle cell fate commitment 18816853 Process
21380 GO:0043410 IMP involved_in positive regulation of MAPK cascade 20807544 Process
21380 GO:0043587 IMP involved_in tongue morphogenesis 18816858 Process
21380 GO:0044344 IMP involved_in cellular response to fibroblast growth factor stimulus 20807544 Process
21380 GO:0045596 IMP acts_upstream_of_or_within negative regulation of cell differentiation 19745164 Process
21380 GO:0045893 IDA acts_upstream_of_or_within positive regulation of DNA-templated transcription 15175244,15703190,15843409,16684884 Process
21380 GO:0045944 IDA involved_in positive regulation of transcription by RNA polymerase II 16556915,21177346 Process
21380 GO:0045944 IGI acts_upstream_of_or_within positive regulation of transcription by RNA polymerase II 16556915,20463296 Process
21380 GO:0045944 IMP involved_in positive regulation of transcription by RNA polymerase II 20122914 Process
21380 GO:0048384 IMP involved_in retinoic acid receptor signaling pathway 18816858 Process
21380 GO:0048514 IMP acts_upstream_of_or_within blood vessel morphogenesis 11239417 Process
21380 GO:0048538 IMP acts_upstream_of_or_within thymus development 17916582 Process
21380 GO:0048644 IGI acts_upstream_of_or_within muscle organ morphogenesis 19531352 Process
21380 GO:0048665 IGI acts_upstream_of_or_within neuron fate specification 15064766 Process
21380 GO:0048665 IMP acts_upstream_of_or_within neuron fate specification 15084464 Process
21380 GO:0048701 IMP acts_upstream_of_or_within embryonic cranial skeleton morphogenesis 15190012 Process
21380 GO:0048752 IGI acts_upstream_of_or_within semicircular canal morphogenesis 19855134 Process
21380 GO:0048844 IGI acts_upstream_of_or_within artery morphogenesis 19700621,19855134,24821700 Process
21380 GO:0048844 IMP acts_upstream_of_or_within artery morphogenesis 11242110 Process
21380 GO:0050673 IMP acts_upstream_of epithelial cell proliferation 17074316,19233155,20816801 Process
21380 GO:0050679 IMP acts_upstream_of_or_within positive regulation of epithelial cell proliferation 17074316,17825816,19233155,20816801 Process
21380 GO:0050679 IMP involved_in positive regulation of epithelial cell proliferation 18231833 Process
21380 GO:0060022 IMP acts_upstream_of_or_within hard palate development 30121012 Process
21380 GO:0060037 IGI acts_upstream_of_or_within pharyngeal system development 21364285 Process
21380 GO:0060037 IMP acts_upstream_of_or_within pharyngeal system development 16141220 Process
21380 GO:0060037 IMP involved_in pharyngeal system development 21177346 Process
21380 GO:0060325 IMP acts_upstream_of_or_within face morphogenesis 20501333 Process
21380 GO:0060415 IMP acts_upstream_of_or_within muscle tissue morphogenesis 19531352 Process
21380 GO:0060982 IMP acts_upstream_of_or_within coronary artery morphogenesis 18583714 Process
21380 GO:0070166 IMP acts_upstream_of_or_within enamel mineralization 19233155 Process
21380 GO:0071300 IEP involved_in cellular response to retinoic acid 18816858 Process
21380 GO:0071600 IMP acts_upstream_of_or_within otic vesicle morphogenesis 17074316 Process
21380 GO:0072513 IDA acts_upstream_of_or_within positive regulation of secondary heart field cardioblast proliferation 19745164 Process
21380 GO:0090103 IGI involved_in cochlea morphogenesis 18231833 Process
21380 GO:0090103 IMP acts_upstream_of_or_within cochlea morphogenesis 17825816 Process
21380 GO:0097152 IMP involved_in mesenchymal cell apoptotic process 18231833 Process
21380 GO:1904888 IGI involved_in cranial skeletal system development 19247433 Process
21380 GO:2000027 IGI acts_upstream_of_or_within regulation of animal organ morphogenesis 19389367 Process
21380 GO:2000027 IMP acts_upstream_of_or_within regulation of animal organ morphogenesis 17164259,19389367 Process
21380 GO:2001037 IMP involved_in positive regulation of tongue muscle cell differentiation 18816858 Process
21380 GO:2001054 IGI involved_in negative regulation of mesenchymal cell apoptotic process 18231833 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
21380 GO:0001162 IDA enables RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding 16556915 Function
21380 GO:0001228 IDA enables DNA-binding transcription activator activity, RNA polymerase II-specific 16556915 Function
21380 GO:0005515 IPI enables protein binding 20463296,20816801,21177346,22438823,22842189 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
21380 GO:0005634 IDA located_in nucleus 17164259,18816853 Component