Gene Ontology

Gene Info

  • Species:Human (Homo sapiens)
  • GeneID:2192
  • Symbol:FBLN1
  • Description:fibulin 1

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
2192 GO:0001933 IDA involved_in negative regulation of protein phosphorylation 11792823 Process
2192 GO:0007162 IDA involved_in negative regulation of cell adhesion 11792823 Process
2192 GO:0007229 IDA NOT involved_in integrin-mediated signaling pathway 11792823 Process
2192 GO:0070373 IDA involved_in negative regulation of ERK1 and ERK2 cascade 11792823 Process
2192 GO:0072378 IDA involved_in blood coagulation, fibrin clot formation 7642629 Process
2192 GO:1900025 IDA involved_in negative regulation of substrate adhesion-dependent cell spreading 11792823 Process
2192 GO:2000146 IDA involved_in negative regulation of cell motility 11792823 Process
2192 GO:2000647 IDA involved_in negative regulation of stem cell proliferation 11238726 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
2192 GO:0001968 IPI enables fibronectin binding 1400330,9278415 Function
2192 GO:0005178 IPI enables integrin binding 25661773 Function
2192 GO:0005201 IDA enables extracellular matrix structural constituent 2269669 Function
2192 GO:0005509 IDA enables calcium ion binding 9278415 Function
2192 GO:0005515 IPI enables protein binding 11238726 Function
2192 GO:0042802 IDA enables identical protein binding 1400330,9278415,25661773 Function
2192 GO:0042802 IPI enables identical protein binding 25661773 Function
2192 GO:0044877 IPI enables protein-containing complex binding 7642629 Function
2192 GO:0070051 IPI enables fibrinogen binding 7642629 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
2192 GO:0005576 HDA located_in extracellular region 27068509 Component
2192 GO:0005615 HDA located_in extracellular space 20551380 Component
2192 GO:0005615 IDA located_in extracellular space 2269669 Component
2192 GO:0031012 IDA located_in extracellular matrix 2269669 Component
2192 GO:0062023 HDA colocalizes_with collagen-containing extracellular matrix 20551380 Component
2192 GO:0062023 HDA located_in collagen-containing extracellular matrix 25037231,28327460,28675934 Component
2192 GO:0070062 HDA located_in extracellular exosome 23533145 Component
2192 GO:0071953 IDA located_in elastic fiber 7534784 Component