Gene Ontology

Gene Info

  • Species:Human (Homo sapiens)
  • GeneID:2242
  • Symbol:FES
  • Description:FES proto-oncogene, tyrosine kinase

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
2242 GO:0004713 IDA enables protein tyrosine kinase activity 11509660 Function
2242 GO:0004715 IDA enables non-membrane spanning protein tyrosine kinase activity 15485904 Function
2242 GO:0005515 IPI enables protein binding 18046454,21044950,24728074,25852190,32707033 Function
2242 GO:0034987 IDA enables immunoglobulin receptor binding 19001085 Function
2242 GO:0035091 IDA enables phosphatidylinositol binding 19001085 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
2242 GO:0005737 IDA located_in cytoplasm 11339827 Component
2242 GO:0005925 IDA located_in focal adhesion 18046454 Component
2242 GO:0009898 IDA located_in cytoplasmic side of plasma membrane 18046454,19001085 Component
2242 GO:0015630 IDA located_in microtubule cytoskeleton 15485904 Component
2242 GO:0031410 IDA colocalizes_with cytoplasmic vesicle 11339827 Component

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
2242 GO:0008360 IMP involved_in regulation of cell shape 11509660,18046454 Process
2242 GO:0010976 IMP involved_in positive regulation of neuron projection development 15302586 Process
2242 GO:0018108 IDA involved_in peptidyl-tyrosine phosphorylation 11509660,15485904 Process
2242 GO:0030155 IMP involved_in regulation of cell adhesion 11509660 Process
2242 GO:0031116 IMP involved_in positive regulation of microtubule polymerization 15485904 Process
2242 GO:0042127 IMP involved_in regulation of cell population proliferation 11509660 Process
2242 GO:0043304 IMP involved_in regulation of mast cell degranulation 19001085 Process
2242 GO:0045595 IMP involved_in regulation of cell differentiation 15302586 Process
2242 GO:0045639 IMP involved_in positive regulation of myeloid cell differentiation 2656706 Process
2242 GO:0045657 IMP involved_in positive regulation of monocyte differentiation 28389358 Process
2242 GO:0046777 IDA involved_in protein autophosphorylation 7687763 Process
2242 GO:0071305 IMP involved_in cellular response to vitamin D 28389358 Process
2242 GO:2000145 IMP involved_in regulation of cell motility 18046454 Process