GeneID | GO_ID | Evidence | Qualifier | GO_term | Pubmed ID | Category | 22900 | GO:0005515 | IPI | enables | protein binding | 11551959,15030775,31525884 | Function | 22900 | GO:0008656 | IDA | enables | cysteine-type endopeptidase activator activity involved in apoptotic process | 15030775 | Function | 22900 | GO:0032089 | IPI | enables | NACHT domain binding | 15030775 | Function | 22900 | GO:0038187 | IDA | enables | pattern recognition receptor activity | 33542150 | Function | 22900 | GO:0042803 | IDA | enables | protein homodimerization activity | 15030775 | Function | 22900 | GO:0050700 | IPI | enables | CARD domain binding | 11821383 | Function | 22900 | GO:0140608 | IDA | enables | cysteine-type endopeptidase activator activity | 31525884 | Function | 22900 | GO:0140693 | IDA | enables | molecular condensate scaffold activity | 33053349 | Function |
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GeneID | GO_ID | Evidence | Qualifier | GO_term | Pubmed ID | Category | 22900 | GO:0005634 | IDA | located_in | nucleus | 11551959 | Component | 22900 | GO:0005654 | IDA | located_in | nucleoplasm | Component | 22900 | GO:0005737 | IDA | is_active_in | cytoplasm | 24517500 | Component | 22900 | GO:0005737 | IDA | located_in | cytoplasm | 15030775 | Component | 22900 | GO:0032991 | IDA | part_of | protein-containing complex | 11821383 | Component | 22900 | GO:0072559 | IDA | part_of | NLRP3 inflammasome complex | 15030775 | Component |
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GeneID | GO_ID | Evidence | Qualifier | GO_term | Pubmed ID | Category | 22900 | GO:0010804 | IMP | involved_in | negative regulation of tumor necrosis factor-mediated signaling pathway | 11821383 | Process | 22900 | GO:0031665 | IDA | involved_in | negative regulation of lipopolysaccharide-mediated signaling pathway | 11821383 | Process | 22900 | GO:0032088 | IMP | involved_in | negative regulation of NF-kappaB transcription factor activity | 11821383 | Process | 22900 | GO:0032691 | IDA | involved_in | negative regulation of interleukin-1 beta production | 11821383 | Process | 22900 | GO:0032731 | IDA | involved_in | positive regulation of interleukin-1 beta production | 15030775 | Process | 22900 | GO:0043124 | IDA | involved_in | negative regulation of I-kappaB kinase/NF-kappaB signaling | 11551959 | Process | 22900 | GO:0043280 | IDA | involved_in | positive regulation of cysteine-type endopeptidase activity involved in apoptotic process | 11821383,15030775 | Process | 22900 | GO:0051607 | IDA | involved_in | defense response to virus | 33542150 | Process | 22900 | GO:0097264 | IDA | involved_in | self proteolysis | 33542150 | Process | 22900 | GO:0097340 | IDA | involved_in | inhibition of cysteine-type endopeptidase activity | 11821383 | Process | 22900 | GO:0140374 | IDA | involved_in | antiviral innate immune response | 33542150 | Process | 22900 | GO:0140633 | IDA | involved_in | CARD8 inflammasome complex assembly | 31525884,33053349,33420033 | Process | 22900 | GO:1900226 | IDA | involved_in | negative regulation of NLRP3 inflammasome complex assembly | 24517500 | Process |
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