Gene Ontology

Gene Info

• Species:Mouse (Mus musculus)
• GeneID:233979
• Symbol:Tpcn2
• Description:two pore segment channel 2

Function

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
233979	GO:0005245	IMP	enables	voltage-gated calcium channel activity	20495006	Function
233979	GO:0015280	IDA	enables	ligand-gated sodium channel activity	27231233	Function
233979	GO:0072345	IDA	enables	NAADP-sensitive calcium-release channel activity	19557428	Function
233979	GO:0072345	IMP	enables	NAADP-sensitive calcium-release channel activity	20495006,25144390	Function

Component

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
233979	GO:0005764	IDA	located_in	lysosome	20495006,25144390	Component
233979	GO:0005765	IDA	located_in	lysosomal membrane	19557428,32167471	Component
233979	GO:0033162	IDA	located_in	melanosome membrane	27231233	Component

Process

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
233979	GO:0006939	IMP	involved_in	smooth muscle contraction	20547763	Process
233979	GO:0017157	IMP	involved_in	regulation of exocytosis	32167471	Process
233979	GO:0019722	IMP	involved_in	calcium-mediated signaling	25144390	Process
233979	GO:0048086	IDA	involved_in	negative regulation of developmental pigmentation	27231233	Process
233979	GO:0051209	IMP	involved_in	release of sequestered calcium ion into cytosol	20495006,25144390	Process
233979	GO:0051452	IDA	involved_in	intracellular pH reduction	27231233	Process
233979	GO:0075509	IMP	involved_in	endocytosis involved in viral entry into host cell	25722412	Process
233979	GO:0090117	IMP	involved_in	endosome to lysosome transport of low-density lipoprotein particle	25144390	Process