Gene Ontology

Gene Info

  • Species:Rat (Rattus norvegicus)
  • GeneID:24318
  • Symbol:Drd2
  • Description:dopamine receptor D2

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
24318 GO:0001591 IDA enables dopamine neurotransmitter receptor activity, coupled via Gi/Go 2974511,8302280 Function
24318 GO:0005102 IPI enables signaling receptor binding 17145509 Function
24318 GO:0005515 IPI enables protein binding 10391935,12890920,14499480,14617818,14709338,15361545,17472703..... Function
24318 GO:0035240 IMP enables dopamine binding 17174299 Function
24318 GO:0035255 IPI enables ionotropic glutamate receptor binding 17145509 Function
24318 GO:0042802 IPI enables identical protein binding 20813060 Function
24318 GO:0044877 IPI enables protein-containing complex binding 22986162 Function
24318 GO:0097159 IPI enables organic cyclic compound binding 15852061 Function
24318 GO:1901363 IPI enables heterocyclic compound binding 15852061 Function

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
24318 GO:0001666 IMP involved_in response to hypoxia 15681393 Process
24318 GO:0001933 IMP involved_in negative regulation of protein phosphorylation 26277342 Process
24318 GO:0001975 IEP involved_in response to amphetamine 19145071 Process
24318 GO:0002031 IDA involved_in G protein-coupled receptor internalization 14617818 Process
24318 GO:0002092 IMP involved_in positive regulation of receptor internalization 18809670 Process
24318 GO:0006914 IDA involved_in autophagy 26649942 Process
24318 GO:0007188 IDA involved_in adenylate cyclase-modulating G protein-coupled receptor signaling pathway 12086672 Process
24318 GO:0007195 IDA involved_in adenylate cyclase-inhibiting dopamine receptor signaling pathway 2410769 Process
24318 GO:0007212 IDA involved_in dopamine receptor signaling pathway 12121979 Process
24318 GO:0007416 IEP involved_in synapse assembly 10051231 Process
24318 GO:0007616 IMP involved_in long-term memory 17118678 Process
24318 GO:0007626 IMP involved_in locomotory behavior 16530737 Process
24318 GO:0009410 IDA involved_in response to xenobiotic stimulus 1975644 Process
24318 GO:0009636 IEP involved_in response to toxic substance 19576243 Process
24318 GO:0010039 IEP involved_in response to iron ion 19022977 Process
24318 GO:0014854 IEP involved_in response to inactivity 17511973 Process
24318 GO:0016055 IDA involved_in Wnt signaling pathway 17472703 Process
24318 GO:0021756 IEP involved_in striatum development 22015925 Process
24318 GO:0021769 IEP involved_in orbitofrontal cortex development 22015925 Process
24318 GO:0030900 IMP involved_in forebrain development 17175142 Process
24318 GO:0031223 IMP involved_in auditory behavior 17142301 Process
24318 GO:0032147 IDA involved_in activation of protein kinase activity 12086672 Process
24318 GO:0033602 IMP involved_in negative regulation of dopamine secretion 16490190 Process
24318 GO:0035094 IEP involved_in response to nicotine 19406037 Process
24318 GO:0042321 IDA involved_in negative regulation of circadian sleep/wake cycle, sleep 12944496 Process
24318 GO:0042756 IDA involved_in drinking behavior 12944496 Process
24318 GO:0043266 IDA involved_in regulation of potassium ion transport 2162345,8371717 Process
24318 GO:0043408 IDA involved_in regulation of MAPK cascade 12121979 Process
24318 GO:0043666 IMP involved_in regulation of phosphoprotein phosphatase activity 12435803 Process
24318 GO:0045471 IEP involved_in response to ethanol 18536982 Process
24318 GO:0045745 IMP involved_in positive regulation of G protein-coupled receptor signaling pathway 18809670 Process
24318 GO:0045944 IDA involved_in positive regulation of transcription by RNA polymerase II 12388421 Process
24318 GO:0046676 IMP involved_in negative regulation of insulin secretion 18216393 Process
24318 GO:0046717 IDA involved_in acid secretion 8302280 Process
24318 GO:0048678 IEP involved_in response to axon injury 19500946 Process
24318 GO:0050769 IDA involved_in positive regulation of neurogenesis 27638511 Process
24318 GO:0050805 IDA involved_in negative regulation of synaptic transmission 17314300 Process
24318 GO:0051209 IMP involved_in release of sequestered calcium ion into cytosol 8371717 Process
24318 GO:0051481 IMP involved_in negative regulation of cytosolic calcium ion concentration 15681393 Process
24318 GO:0051823 IDA involved_in regulation of synapse structural plasticity 22216301 Process
24318 GO:0070374 IMP involved_in positive regulation of ERK1 and ERK2 cascade 18809670 Process
24318 GO:0090325 IMP involved_in regulation of locomotion involved in locomotory behavior 22394078 Process
24318 GO:0099170 EXP involved_in postsynaptic modulation of chemical synaptic transmission 15175382 Process
24318 GO:0099170 IDA involved_in postsynaptic modulation of chemical synaptic transmission 15175382 Process
24318 GO:1900038 IMP involved_in negative regulation of cellular response to hypoxia 27638511 Process
24318 GO:1900273 IMP involved_in positive regulation of long-term synaptic potentiation 20377617 Process
24318 GO:1901386 IDA involved_in negative regulation of voltage-gated calcium channel activity 2162345 Process

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
24318 GO:0001669 IDA located_in acrosomal vesicle 16924680 Component
24318 GO:0016020 IDA located_in membrane 8302280 Component
24318 GO:0016328 IDA located_in lateral plasma membrane 10391935 Component
24318 GO:0030139 IDA located_in endocytic vesicle 14617818 Component
24318 GO:0030424 IDA located_in axon 12965226 Component
24318 GO:0030425 IDA located_in dendrite 12965226,15224400 Component
24318 GO:0030672 IDA located_in synaptic vesicle membrane 7623147 Component
24318 GO:0036126 IDA located_in sperm flagellum 16924680 Component
24318 GO:0042734 IDA is_active_in presynaptic membrane 18340460 Component
24318 GO:0043197 IDA located_in dendritic spine 7623147 Component
24318 GO:0043204 IDA located_in perikaryon 12965226 Component
24318 GO:0043679 IDA located_in axon terminus 7623147 Component
24318 GO:0045211 IDA is_active_in postsynaptic membrane 18340460 Component
24318 GO:0098978 IDA is_active_in glutamatergic synapse 18340460 Component
24318 GO:0098982 IDA is_active_in GABA-ergic synapse 18340460 Component