Gene Ontology

Gene Info

• Species:Mouse (Mus musculus)
• GeneID:243961
• Symbol:Shank1
• Description:SH3 and multiple ankyrin repeat domains 1

Function

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
243961	GO:0005515	IPI	enables	protein binding	21653829	Function
243961	GO:0030160	IMP	enables	synaptic receptor adaptor activity	18272690	Function
243961	GO:0035255	IPI	enables	ionotropic glutamate receptor binding	15207857,16606358	Function
243961	GO:0098919	IDA	enables	structural constituent of postsynaptic density	18272690	Function
243961	GO:0098919	IEP	enables	structural constituent of postsynaptic density	18272690	Function
243961	GO:0098919	IMP	enables	structural constituent of postsynaptic density	18272690	Function

Component

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
243961	GO:0005886	IDA	located_in	plasma membrane	15207857	Component
243961	GO:0014069	IDA	is_active_in	postsynaptic density	18272690	Component
243961	GO:0014069	IDA	located_in	postsynaptic density	21144999	Component
243961	GO:0030425	IDA	located_in	dendrite	21940441	Component
243961	GO:0043005	IDA	located_in	neuron projection	21795692	Component
243961	GO:0043197	IDA	located_in	dendritic spine	15207857	Component
243961	GO:0045211	IDA	colocalizes_with	postsynaptic membrane	15207857	Component
243961	GO:0045211	IDA	located_in	postsynaptic membrane	15950311	Component
243961	GO:0060076	IDA	located_in	excitatory synapse	18272690	Component
243961	GO:0098685	IDA	is_active_in	Schaffer collateral - CA1 synapse	18272690	Component
243961	GO:0098685	IEP	is_active_in	Schaffer collateral - CA1 synapse	18272690	Component
243961	GO:0098685	IMP	is_active_in	Schaffer collateral - CA1 synapse	18272690	Component
243961	GO:0098978	IDA	is_active_in	glutamatergic synapse	18272690	Component
243961	GO:0098978	IEP	is_active_in	glutamatergic synapse	18272690	Component
243961	GO:0098978	IMP	is_active_in	glutamatergic synapse	18272690	Component

Process

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
243961	GO:0007616	IMP	involved_in	long-term memory	18272690	Process
243961	GO:0008306	IMP	involved_in	associative learning	18272690	Process
243961	GO:0032232	IDA	acts_upstream_of_or_within	negative regulation of actin filament bundle assembly	19208628	Process
243961	GO:0035176	IMP	involved_in	social behavior	21695253	Process
243961	GO:0035418	IMP	involved_in	protein localization to synapse	18272690	Process
243961	GO:0042048	IMP	involved_in	olfactory behavior	21695253	Process
243961	GO:0046959	IMP	involved_in	habituation	21695253	Process
243961	GO:0050804	IDA	involved_in	modulation of chemical synaptic transmission	18272690	Process
243961	GO:0050804	IEP	involved_in	modulation of chemical synaptic transmission	18272690	Process
243961	GO:0050804	IMP	involved_in	modulation of chemical synaptic transmission	18272690	Process
243961	GO:0050885	IMP	involved_in	neuromuscular process controlling balance	20868654	Process
243961	GO:0060013	IMP	involved_in	righting reflex	21695253	Process
243961	GO:0060997	IMP	involved_in	dendritic spine morphogenesis	18272690	Process
243961	GO:0071625	IMP	involved_in	vocalization behavior	21695253	Process
243961	GO:2000311	IMP	involved_in	regulation of AMPA receptor activity	18272690	Process
243961	GO:2000463	IMP	involved_in	positive regulation of excitatory postsynaptic potential	18272690	Process